IUBio

Serial lesions, ischemic preconditioning, etc.

Christopher Hatton Hatton at ifn-magdeburg.de
Wed Mar 12 06:59:31 EST 1997


F. Frank LeFever wrote:
> 
> Still interested.  (no response yet)   Also, ANY truly chronic studies
> even if only one trauma  (posted longer query re chronic studies--but
> don't see it!)
> 
> Frank

(sorry snipped the question)

WE have found, but not yet published that a short 1-2 mins burst of
focal cerebral ischaemia, 1 week before the main prolonged ischaemia
that we actually see a decrease in hippocampal neuronal cell death,
however we haven't set up the learning and memory paradigms properly to
see the effects of our compounds as

 a) Neuroprotective agents,
 b) new memory formation "enhancers" for what of a better word.

However my boss has a couple of paper on this subjects but shes not
here, doesn't read this ng and her filing cabinett is locked (what a
bummer eh)

hope this at least helps a little,

yours

Christopher Hatton


BL-Institut für Neurobiologie
Magdeburg
Germany



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