IUBio

ischemic preconditioning, 1 week delay

F. Frank LeFever flefever at ix.netcom.com
Wed Mar 12 21:59:25 EST 1997


In <33269AA3.324B at ifn-magdeburg.de> Christopher Hatton
<Hatton at ifn-magdeburg.de> writes: 
>
>F. Frank LeFever wrote:
>> 
>> Still interested.  (no response yet)   Also, ANY truly chronic
studies
>> even if only one trauma  (posted longer query re chronic
studies--but
>> don't see it!)
>> 
>> Frank
>
>(sorry snipped the question)
>
>WE have found, but not yet published that a short 1-2 mins burst of
>focal cerebral ischaemia, 1 week before the main prolonged ischaemia
>that we actually see a decrease in hippocampal neuronal cell death,
>however we haven't set up the learning and memory paradigms properly
to
>see the effects of our compounds as
>
> a) Neuroprotective agents,
> b) new memory formation "enhancers" for what of a better word.
>
>However my boss has a couple of paper on this subjects but shes not
>here, doesn't read this ng and her filing cabinett is locked (what a
>bummer eh)
>
>hope this at least helps a little,
>
>yours
>
>Christopher Hatton
>
>
>BL-Institut für Neurobiologie
>Magdeburg
>Germany

One week is shorter than I'm looking for, but it does seem longer than
the interval most use.  I'd be interested in seeing her papers and
anything less formal also.

My FAX:  usa (914) 947-3350

F. Frank LeFever, Ph.D.
Helen Hayes Hospital
West Haverstraw, NY 10993, USA



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