In <Pine.NEB.3.95.970313200718.19694A-100000 at callisto.uwinnipeg.ca>
Michael Roberts <mroberts at callisto.uwinnipeg.ca> writes:
>>>On 12 Mar 1997, windows 95 user wrote:
>>> I have read with great interest of the studies by Rink et al of
evidence of
>> apoptotic cell death.
>> My question is : is the bcl-2 gene which is an apoptotic suppressor
gene
>> induced in traumatic brain injury
>>>>>>>I believe bcl-2 would not be involved in damage resulting from
traumatic
>brain injury, as this injury would be more likely to involve necrosis
than
>apoptosis. Perhaps it would be active in the recovery process while
>aberrant connections are weeded out.
>>-mike
>
re necrosis vs. apoptosis in brain injury: might depend on severity of
injury, distance of cells from focus of trauma, etc.; and not only "as
the crow flies" but according to some aspects of brain organization.
It's late and I don't have references right at hand, but may try to
follow with more details.
Frank LeFever
New York Neuropsychology Group