Hello Boris777,
>please email or post if you'd like references for what i've written (i
^^^^
>don't have them nearby right now).
That would be good of you. I`m sure I won`t be the only one
interested.
>i hope we find that the best ways to stimulate neurogenesis are not
>through pharmacological intervention, but that's my own view...
Useful maybe to persuade people who need them to take/stay on SSRI`s
(As in `And, Winifred, they`re good for your brain, too!`)
In article <8b6ill$9nf$1 at nnrp1.deja.com>, boris777 at my-deja.com writes
>In article <38D333EC.186DFBE8 at primus.com.au>,
>Ian McLeod <ian_mcleod at primus.com.au> wrote:
>>>>>> Brian Scott wrote:
>>>> This is not good news for the drug education bodies. Does this mean that
>> drugs such as amphetamines can actually help people? Or am I mistaking
>> amphetamines for something else?
>>amphetamines have a decidedly non-neurogenetic effect. methamphetamine
>is one of the more potent serotonergic and dopaminergic neurotoxins.
>its neurotoxic properties appear to have more to do with free radical
>generation than its ability to stimulate serotonin or dopamine release.
>>>>>> Could we facilitate neurogenesis without drugs? Meditation, anything that may
>> reduce stress and increase seratonin.
>>>> >
>> > R.S. Duman reported at a recent Society for Neuroscience meeting that
>>i worked next door to ron duman from 1998-1999 and the theory that was
>emerging from the lab was that ECS and SSRIs stimulate CREB mediated
>transcription of Brain Derived Neurotrophic Factor (BDNF) which has
>rather well-documented neuroprotective ability, and may also be
>implicated in neurogenesis, though that latter link still appears to be
>weak.
>>also, fred gage's group has shown that simply running (in rats) or
>living in an environment with more varied stimulation than a stainless
>steel cage will increase neurogenesis too....i hope we find that the
>best ways to stimulate neurogenesis are not through pharmacoligcal
>intervention, but that's my own view...
>>please email or post if you'd like references for what i've written (i
>don't have them nearby right now).
>>peas,
>boris
>>> > several antidepressant drugs as well as electroconvulsive shock also
>> > increase neurogenesis in the dentate gyrus. It's likely that anything
>> > that increases serotonin action will increase neurogenesis by an effect
>> > on proliferation of the progenitor cells.
>> >
>> > --
>> >
>> > Brian Scott
>> > brians at eol.ca>> > brians at interlog.com>> >
>> > "In other studies you go as far as others have gone before you, and
>> > there is nothing more to know; but in scientific pursuit there is
>> > continual food for discovery and wonder." - Victor Frankenstein
>> > (from Mary Shelley's Frankenstein, 1818)
>>>>>>>Sent via Deja.com http://www.deja.com/>Before you buy.
--
jan
