before i get "buzzed", "special topological homeomorphism" and
"internal frame of reference", while not the same, are two sides of
the same coin.
ken
Kenneth Collins wrote in message ...
>Yup. I stand on what I've posted.
>>the pertinent info is given on pA3-14, AoK, Ap3 [ref. Human
>Neuroanatomy, 8th Ed., 1983 [page numbers cited below]]:
>>"In the dorsal horn of the spinal cord, the terminations of noxious
>and non-noxious sensory fibers are mapped inversely with respect to
>each other (in a topologically-distributed antagonistic fashion) (p.
>245, diagram p. 246).
>>Short fibers from spinal lamina II (substantia gelatinosa) enter the
>zone of Lissauer (at the tip of the dorsal horn) and project
>ipsilaterally within the spinal cord, synapsing one or more times
>before projecting contralaterally into the (ascending) spinothalamic
>tract (p. 275)."
>>the inverse topological mapping noxious and non-noxious fiber
>terminations is a dead-give-away with respect to 'moving away from'
>pain. [I wrote it into the paper in this way in order to show how
>rigorously the internal frame of reference [IFR] maintains its
>structural integrity, with respect to TD E/I-minimization,
>=throughout= the CNS. This's one of numerous 'nuggets' that I put
>into AoK, deliberately, to reward the reading of Professionals, even
>though the paper was written as an introduction for
>non-Professionals.
>>[does this New Scientist article mean that all the 'nuggets' have
>been 'missed' by the Pros? C fibers are one of the main things
>in-there. it's non-sense to attribute them exclusively to stroking's
>'feel-good' stuff (no 'snide' remarks please :-).]
>>k. p. collins
>>Kenneth Collins wrote in message ...
>>"Scientists reveal the secret of cuddles", 19:00 28 July 02,
>>NewScientist.com news service
>>>>http://www.newscientist.com/news/news.jsp?id=ns99992598>>>>for now, i stand on what i posted. the bi-directional
>inter-segmental
>>relays just have to convey information to the closest intact
>>spinothalamic entry-'point'.
>>>>interpretation that the short relays in the spinal [dorsal] gray
are
>>in-there solely for the purpose of 'feeling-good' as a result of
>>'being stroked' is extreme. (in my case, they'd be a complete
>'waste'
>>:-)
>>>>i've always viewed them as constituting a 'pliable' pathway that's
>>tunable-to-task, providing 'background', and spinal-'level'
>>convergence [TD E/I-minimization].
>>>>i'll reread, and post a follow-up, one way or the other.
>>>>['interesting' that this link is getting a lot of hits today :-]
>>>>k. p. collins
>>>>Kenneth Collins wrote in message ...
>>>hi, Mark.
>>>>>>there're several 'pathways involved in what's been referred to as
>>'pain'.
>>>[for those who have it, there is a basic overview of these
>pathways,
>>and
>>>their topological-mapping [within a larger 'enumeration', with
>>respect to
>>>more than 'pain'], in AoK, Ap3.]
>>>>>>one of these 'pathways' occurs via many bi-directional relays
>within
>>the
>>>'gray-matter' of the spinal column.
>>>>>>any divergence from 'normal' activation within this pathway is
>>experienced
>>>as 'pain' be-cause it constitutes a TD E/I-up condition within
this
>>pathway
>>>which is part of the 'pain' sub-system.
>>>>>>the 'many-relay' nature of this pathway is 'engineered' with
>>precisely the
>>>sort of tissue-damage that you've described, and the overall
>>'engineering'
>>>of the nervous system as a =generalized= processor is Obvious.
>>>>>>this is a pathway that 'calculates' with respect to =any= possible
>>>tissue-damage, and performs its function, regardless.
>>>>>>if there's something 'normal' that's 'missing', the pathway
>>'calculates' the
>>>inherent topology of the resultant "tuning-precision void" [TD
>>E/I(up)], and
>>>=still=, carries the correct [topologically-mapped] information
>into
>>the
>>>CNS, which enables survival-enhancing behavioral manifestation.
[in
>>the same
>>>way as is discussed in the 'sprained-ankle example in AoK's "Short
>>Paper"
>>>section [footnote 11 in the paper version].
>>>>>>we experience 'pain' as an inducement to redistribute the
>activation
>>of our
>>>effectors during behavior. such 'strategic' redistribution of
>>muscular
>>>activation 'shifts-the-burden' away from injured tissue,
>>simultaneously
>>>allowing what remains fully-functional to work in attempts to
>>survive, and,
>>>over a longer 'time' course, allowing the injured tissue a
>>>relatively-optimized opportunity to 'heal'.
>>>>>>as is discussed in AoK, all of this is made-possible via the
>elegant
>>>topological 'twists and turns' of the nervous system's "special
>>topological
>>>homeomorphism".
>>>>>>if you don't have AoK, and want a copy, msg. privately [runs under
>>DOS or
>>>Windows].
>>>>>>k. p. collins
>>>>>>Mark Zarella wrote in message
<82tZ8.572162$cQ3.54221 at sccrnsc01>...
>>>>Even after rereading the analgesia chapter in Kandel, I'm having
>>trouble
>>>>understanding the mechanism in which the sensation of pain can be
>>>>experienced in areas where there's no other sensory activity.
For
>>>instance,
>>>>if a peripheral nerve is severed and a limb or digit then becomes
>>numb to
>>>>all forms of sensory activity, how then can pain still be
detected
>>in these
>>>>areas?
>>>>>>>>More specifically, about 2 weeks ago I was in an accident where I
>>sustained
>>>>a rather deep laceration in the upper wrist / lower hand
resulting
>>in the
>>>>ulnar nerve becoming severed, as well as part of the median nerve
>>(and a
>>>>tendon and artery, which were also repaired). The nerves were
>>reattached,
>>>>but theres no feeling (proprioreceptive or cutaneous) in 3
fingers
>>and
>>>parts
>>>>of the upper palm. However, there's the sensation of "shooting
>>pain" at
>>>the
>>>>fingertips and elsewhere in these areas. How is that possible?
>>Could it
>>>be
>>>>a result of feedback with adjacent nerves in the relay sites and
>>cns? What
>>>>about distal portions of the nerve beginning to regain function
>but
>>not yet
>>>>being "remapped" after reattachment? As you can see, I have no
>>ideas.
>>>>Kandel's book touches on this sort of phenomenon, but nothing
>>specific
>>>>enough to answer this type of question.
>>>>>>>>Any insights are appreciated.
>>>>>>>>- Mark Zarella
>>>>>>
