I thought readers of bionet.neuroscience might be interested in this
book. For more information, please visit
http://mitpress.mit.edu/0262194732/ Thank you!
Best,
David
The Dynamic Neuron
John Smythies
The traditional model of synapses as fixed structures has been replaced
by a dynamic one in which synapses are constantly being deleted and
replaced. This book, written by a leading researcher on the
neurochemistry of schizophrenia, integrates material from neuroscience
and cell biology to provide a comprehensive account of our current
knowledge of the neurochemical basis of synaptic plasticity.
The book presents the evidence for synaptic plasticity, an account of
the dendritic spine and the glutamate synapse with a focus on redox
mechanisms, and the biochemical basis of the Hebbian synapse. It
discusses the role of endocytosis, special proteins, and local protein
synthesis. Additional topics include volume transmission, arachidonic
acid signaling, hormonal modulation, and psychological stress. Finally,
the book considers pharmacological and clinical implications of current
research, particularly with reference to schizophrenia and Alzheimer's
disease.
John Smythies is Director of the Division of Neurochemistry, Center for
Brain and Cognition, University of California, San Diego; Senior
Research Fellow, Institute of Neurology, Queen Square, London; and
Visiting Professor, Department of Psychiatry, Harvard Medical School.
6 x 9, 168 pp., 15 illus., cloth, ISBN 0-262-19473-2
A Bradford Book
