IUBio

Mammalian Genomic Organisation

Gary Paterson g.paterson at bio.gla.ac.uk
Tue Aug 20 07:32:26 EST 2002


I have perfromed RACE experiments which identify sequences that lie
within an a very large intron that separates exons 3 and 4 of the gene I
am studying.  The RACE fragments contain no ORFs.  One possiblity is
that the fragments represent UTRs of splice variants.  However, I was
wondering whether there any examples in mammals in which the genetic
structure of unrelated genes overlap, ie use different strands over the
same region to encode a protein.  I know viruses do this quite alot but
am not aware that mammals make use of this strategy.

please help!
Gary




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