IUBio

High Resolution Intracellular Recordings?

Lance Sherman lancesherman at insightBB.com
Thu Sep 4 10:25:16 EST 2003


to the poster
and the two, above, responders:

much thanks for reminding me why i read this ng


"yan king yin" <y.k.y at lycos.com> wrote in message
news:72de81ae.0309031548.39b66b2d at posting.google.com...
> Hi Everyone =)
>
> I'm trying to find intracellular recordings of the soma of
> in vivo neurons, with *temporal* resolutions in the sub-ms
> range (the finer the better). What I want to see is how the
> spatial and temporal integration actually take place in action.
> Any web page, paper etc...?
>
> I've read from Koch's "Biophysics of Computation" that it
> takes about 64 EPSP inputs *at* the soma close together to
> generate an action potential. (The threshold being about 16mV
> above resting potential and each EPSP typically around 0.3mV).
>
> Is it possible to actually discern individual contributions
> of EPSPs from such recordings? What about background noise
> that is not from EPSPs?
>
> Thanks a lot!
> Yan King Yin
> My Home Page -- http://www.geocities.com/Softuploading/Index.htm





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