"David Longley" <David at longley.demon.co.uk> wrote in message
news:ixlTTGLPtbX$EwqY at longley.demon.co.uk...
| In article
| <yQY6b.130812$0v4.9535784 at bgtnsc04-news.ops.worldnet.att.net>,
KP_PC
| <k.p.collins at worldnet.att.net> writes
| >"Bill Pascoe" <Bill.Pascoe at newcastle.edu.au> wrote in message
| >news:3F568339.1060609 at newcastle.edu.au...| >| [...]
| [...]
| Thus, naloxone suppressed pellet eating
| if the pellets were novel and if naloxone was
| administered before eating tests. The results
| suggest naloxone enhances neophobic
| effects of novel foods and that suppression
| of novel pellet eating is not due to enhanced
| effects of novelty of apparatus cues or to
| conditioned taste aversion.
|| Reference
|| FRENK, H & ROGERS G.H. (1979) The suppressant effects of naloxone
| on food and water intake in the rat.
| Behav. Neural. Biol, 26, 23-40.
|| PROCEEDINGS OF THE BRITISH PHARMACOLOGICAL SOCIETY (BPS)
| 1-3 April 1981
| (Also British J Pharmacology 1981)
| [...]
An example of where I'm coming from:
The initial administration of nalaxone could
have =generalized= ramifications,
[a 'shotgun' impact] which, thereafter,
became TD E/I-minimized to a degree
that allowed the subjects to 'learn' that the
initial generalized thing was not specific
with respect to eating. So they go ahead
and eat, while re-experiencing the non-
TD E/I-minimized remnant of the general-
ized effect of neuropharmacological
intervention.
Such stuff can be controlled for via coupled
automated standardized behavioral observa-
tion regimes - maze-running, novelty-seeking,
exercise wheel usage, escape -behavior, etc.,
all while subject to the neuropharmacological
intervention.
The need for such generalized control regimines
is what underpinned my call [AoK, Ap3] for dev-
elopment of neural-topology keyed experimental-
result databasing.
If behavioral observations were included in such
a database, =convergent= 'pictures' of the nuances
of this or that neuropharmacological intervention
would rapidly [after a technological-'familiarization'
period [Neuroscience-groupwise TD E/I-mini-
mization]] develop.
Without such a database, important observational
nuances =always= 'fall through the cracks' of indi-
vidual Experimenters' focusses [which goes back
to my long-former discussions of the need to
experience widely].
Further note: I admit that I 'reacted' in a biased
way to David's post, because of qualities of our
past 'interaction'. I was Wrong in that, but, other
than that, stand on what I've posted.
k. p. collins
