IUBio

DNA-Tuning [was Re: The Nonlinearity of Perspective [___]

KP_PC k.p.collins at worldnet.att.net
Wed Sep 24 20:05:54 EST 2003


In this post, I'll address the BIG-PICTURE.

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The big-picture:

The genetic material provides the 'blue print'
for a generalized processor.

Beginning pre-natally, experience tunes this
generalized processor as follows.

Early-on, nervous system function is highly-
generalized ["newborn Infants are the most-
intelligent Beings on the face of the planet" -
their adabtability is maximally-generalized].

In this 'stage' of development, the energy-
dynamics that I've been discussing in this
thread occur relatively-haphazardly.

As a consequence of this early, relatively-
disordered functionality, the nervous sys-
tem receives feedback from theit host org-
anism's external experiential environment.

This feedback occurs in the form of what,
in NDT, is referred to as "TD E/I" [the ratio
of Topologically-Distributed Excitation to
Inhibition]. "TD E/I" is =not= just EPSP and
IPSP, etc., but is the infinitely-divisible
[continuous] 'Coulomb force' and its action
with respect to WDB2T.

Everything within nervous systems 'recognizes'
TD E/I.

Thus, as an individual experiences, a general-
ized convergence occurs in which, for instance.
3-D distributions of ion gates gradually becomes
optimized with respect to TD E/I-minimization.

In this way, the activation of the ion gates, and
their collective 'Coulomb force' interactions
with the genetic material converges.

That is, the genetic material [DNA] does not
'dictate' anything other than the functional
strategy for minimizing TD E/I.

Early-on, DNA-RNA activation is relatively
disordered. But as experience ensues,
DNA-RNA activation becomes progressively
more-ordered, in a way that's rigorously-
correlated to TD E/I-minimization.

That is, all of the neural Topology, right down
to the infinitely-divisible 'Coulomb force' itself,
is tunable with respect to TD E/I-minimization.

The strategic-positioning of each 'scrap' of
the neural Topology is tunable with respect to
TD E/I-minimization.

Therefore =everything= is structurally adjusted
so that the DNA-RNA will be activated in the
TD E/I(down) direction.

This position is Testable, for instance, by a
study of the endoplasmic reticulum over the
course of development.

NDT Predicts that modifications to the endo-
plasmic reticulum will exhibit observable
increases in order as a subject develops to
maturity.

NDT holds that, no matter where one looks
within nervous systems, or at what scale one
so observes, this augmentation of order,
which rigorously 'reflects' TD E/I-minimization,
will be Observable.

It is =this= structural tuning that acts upon the
genetic material to direct it with respect to
external experiential energydynamics.

This relationship is like a "you're getting
hotter" guessing game that begins with an
alphabed and has the goal of discovering a
word or a phrase.

Feedback from the game's questioner
guides convergence upon the sought-after
sequence of letters of the alphabet and
spaces [if the goal of the game is a phrase].

The fundamental stuff is maximally-generalized,
but the external experiential feedback ["You're
getting warmer [hot]." "You're getting cooler
[cold]."] determines the internal dynamics.

Is this clear?

Via TD E/I-minimization, experience 'picks the
genetic material up by its bootstraps'.

'Intelligence' is in the supersystem as a whole.

All any 'element' 'knows' is how to respond to
the 'Coulomb forces' that it experiences,
and all of this 'knowing' derives in the
SSW<->UES harmonics of which an 'element'
is comprised.

Get it?

The genetic material defines the =generalized=
processor that acts, as above, to self-organize
in ways that converge upon TD E/I-minimization-
useful activation of the genetic material.

This self-organization takes the form of TD E/I-
minimization-correlated =throughout= the entire
extent of the neural Topology, at all scales.

Other matter, while on "K. P." Duty last night, I
realized that, in its 'spheroidal' architecture, the
endoplasmic reticulum constitutes a physical
embodiment of the "shelling" sub-phase of the
SSW<->UES harmonics, with the awesomely-
functional added capability of being tunable and
selectively permeable - high-'engineering' founded
in the Fundamental stuff that's Reified in TH :-]

It's as a flood - the ribosomes' two-'sphere' structure
repeats the 'theme', and is awesomely-capable
with respect to the DNA-RNA-tuning stuff that I've
been discussing in this thread. The ribosomal
'spheres' are literally little 'Coulomb force' 'lenses' :-]

Pleace =Correct= me if I'm wrong [my basic Biology
Text dates back to 1972 - can't afford to purchase a
new one] the ribosomes also move upon the rough
endoplasmic reticulum(?) If so, this'd enable
awesomely-enhanced tuning.

Then the golgi apparati have a "concave" surface -
'concave mirrors' that reflect' [refract] the 'Coulomb
force'(?) If so, more awesomely-enhanced DNA-RNA
tuning toward TD E/I-minimization, but in an 'outward-
looking' way - with respect to the locating of the 'ion'
gates, cytoskeleton structur and dynamic conformational
tuning, etc., which feedsback into the ongoing
DNA-RNA tuning.

It's as a flood :-]

I can see that the 'time' has finally come that I've
accumulated sufficient Fundamental stuff to make-
practical a serious study of "molecular" stuff.

I Hope 'October' happens.

'My cup overfloweth." :-]

ken [k. p. collins]





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