[Neuroscience] is there any substance in a neuron which would
be enhanced or increased at spiking and would decrease or attenuate
after spiking in a period over 10 to 100 milliseconds?.
tongz from rpi.edu
via neur-sci%40net.bio.net
(by tongz from rpi.edu) Fri May 18 22:54:00 EST 2007
Calcium is responsible for the exocytosis of the synaptica vessles
holding neurotransmitters, so there should be a noticeable increase in
calcium immediately prior to and during a spike. This would only be
apparent in the tip of the axon, near the synpatic cleft. How large this
concentration is I'm not sure though, and it would appear that calcium
concentrations only last for a few milliseconds before being taken back up.
I'm still new to the biology of the brain but I'm thinking it may be
difficult for you to find a substances that lasts that period of time and
is caused by a spike. Neurons are capable of firing every 7-15 ms. I
would hazard a guess that most neurons fire somewhere in that frequency.
Should a high concentration of something build up every time a neuron
fires without being metabolized or taken back up in a prompt manner, it
could be potentially hazardous for the cell. Calcium, for instance, is
taken back up very promptly so that it doesn't cause damage to the cell
and can be released again during the next spike.
But again, I'm very new to neuroscience, so it is entirely possible I'm
quite wrong :)
Cheers,
-Zachary Tong
==============Original message text===============
On Fri, 18 May 2007 20:28:52 EDT "¶Ðñ" wrote:
Hi everyone, I've got a question.
Is there any substance in a neuron which would be enhanced or increased at
spiking and would decrease or attenuate after spiking in a period over 10 to
100 milliseconds?
Thanks very much
regards
<HTML><BODY><br clear=all><br>-- <br>May the force be with you<br>Dong
Xu<br>Biology Department, Xiamen University<br>Fu Rong 104,Xiamen
University<br>Mobile:86-13666035134
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