From owner-structural-nmr@net.bio.net Mon Jul 04 23:00:00 1994
Path: biosci!HELIX.NIH.GOV!bhardy
From: bhardy@HELIX.NIH.GOV (Barry J. Hardy)
Newsgroups: bionet.structural-nmr
Subject: NMR: Gordon conference Net chat
Date: 5 Jul 1994 06:02:28 -0700
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NMRers,
     I'm just wondering if there are other NMR group members out there
who are going to this July's NMR Gordon conference. If so, would you be 
interested in an informal discussion there of NMR-related internet activities?
That latter could include, for example, promoting increased use of the 
group, interdisciplinary electronic publishing of structural biology
research, electronic conferencing, the Web etc. If so send me
an email and we'll get together there.
Barry J. Hardy


From owner-structural-nmr@net.bio.net Mon Jul 04 23:00:00 1994
Path: biosci!HELIX.NIH.GOV!bhardy
From: bhardy@HELIX.NIH.GOV (Barry J. Hardy)
Newsgroups: bionet.structural-nmr
Subject: NMR: Electronic Conference for 1995
Date: 5 Jul 1994 05:57:24 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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NMRers,
     I'll suggest aloud to the group that it would be very worthwhile
to have an NMR-group related electronic conference coupled to newsgroup
discussions. It should be possible to organize such an event for sometime
in 1995. Perhaps the most interesting event would be an intergroup
conference which included the bionet molecular modeling
and crystalography groups. Discussion?       
Barry J. Hardy


From owner-structural-nmr@net.bio.net Mon Jul 04 23:00:00 1994
Path: biosci!agate!spool.mu.edu!howland.reston.ans.net!EU.net!ub4b!idefix.CS.kuleuven.ac.be!infoserv.rug.ac.be!allserv!kboulez
From: kboulez@allserv.rug.ac.be (Kris Boulez)
Newsgroups: bionet.structural-nmr
Subject: Re: NMR: Gordon conference Net chat
Date: 5 Jul 1994 14:50:49 GMT
Organization: University of Ghent, Belgium
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X-Newsreader: TIN [version 1.2 PL2]

Barry J. Hardy (bhardy@HELIX.NIH.GOV) wrote:
: NMRers,
:      I'm just wondering if there are other NMR group members out there
: who are going to this July's NMR Gordon conference. If so, would you be 
: interested in an informal discussion there of NMR-related internet activities?
: That latter could include, for example, promoting increased use of the 
: group, interdisciplinary electronic publishing of structural biology
: research, electronic conferencing, the Web etc. If so send me
: an email and we'll get together there.
: Barry J. Hardy


Hello,

I want to ask the same question for the ICMRBS conference in August 
in the Netherlands.

--
Kris Boulez
Biomolecular NMR unit
University of Gent
Belgium

From owner-structural-nmr@net.bio.net Tue Jul 05 23:00:00 1994
Path: biosci!agate!sprite.berkeley.edu!shirriff
From: shirriff@sprite.berkeley.edu (Ken Shirriff)
Newsgroups: bionet.structural-nmr
Subject: Re: PDB Viewers....
Date: 6 Jul 1994 21:27:39 GMT
Organization: University of California, Berkeley
Lines: 13
Distribution: world
Message-ID: <2vf7kb$n9k@agate.berkeley.edu>
References: <9406271534.AA21450@cadmium.csb.yale.edu>
NNTP-Posting-Host: hijack.cs.berkeley.edu

In article <9406271534.AA21450@cadmium.csb.yale.edu>,
Kevin Gardner <gardner@CADMIUM.CSB.YALE.EDU> wrote:
>6.  RASMOL & TKRASMOL by Roger Sayle and Ken Shirriff respectively
>	TkRasMol incorporates a tk-based frontend onto the
>	RasMol program, making it somewhat easier to use for those
>	who prefer using GUIs over command-line interfaces.  Contact
>	Ken Shirriff (shirriff@sprite.berkeley.edu) for more information.

Please note that I have abandoned tkrasmol, as I don't have the time to
support it.  You can ftp it from sprite.Berkeley.EDU in tkrasmol.tar.Z if
you really want it, but I can't help with bugs or anything.

Ken Shirriff				shirriff@cs.Berkeley.EDU

From owner-structural-nmr@net.bio.net Wed Jul 13 23:00:00 1994
Path: biosci!MED.UNC.EDU!sheng
From: sheng@MED.UNC.EDU (Sheng Zhong)
Newsgroups: bionet.structural-nmr
Subject: Laminar Pulses
Date: 14 Jul 1994 09:41:06 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
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Would any one here please comment on generating Steven L. Patt's Frequency 
shifted Laminar Pulses on AMX. We are trying to fake the fourth channel (C') by 
using this method before getting real fourth channel. I know it is quite straight 
forward to apply this technique on varian 's waveform generator. Any pro and 
cons ?
Thanks in advance.

Dr. Sheng Zhong
Department of Biochemistry & Biophysics
University of North Carolina
sheng@hasty.med.unc.edu

From owner-structural-nmr@net.bio.net Tue Jul 19 23:00:00 1994
Path: biosci!biosci!not-for-mail
From: syllabus@netcom.com (Syllabus Press)
Newsgroups: bionet.structural-nmr,clari.tw.biotechnology,alt.bio.minority,bionet.biology.grasses,bionet.microbiology,bionet.molec-model,uiuc.org.acm.sigbio,bionet.celegans,bionet.announce,bionet.argoforestry
Subject: Higher Education Technology Conference
Date: 20 Jul 1994 16:56:43 -0700
Organization: NETCOM On-line Communication Services (408 261-4700 guest)
Lines: 60
Sender: kristoff@net.bio.net
Approved: bionews-moderator@net.bio.net
Distribution: world
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Xref: biosci bionet.structural-nmr:166 alt.bio.minority:31 bionet.biology.grasses:59 bionet.microbiology:78 bionet.molec-model:44 bionet.celegans:21 bionet.announce:1295

UC-Santa Cruz and Syllabus Press (publishers of Syllabus magazine) are
co-sponsoring a conference on the use of technology in higher education. 
Due to the location of conference, we will be having some diving
activities in Monterey Bay, probably a boat dive and myabe a few beach
dives. Below is a brief synopsis of the conference. 

For either a print or electronic conference registration package, please
contact Syllabus Press via e-mail or or call 800-773-0670. 

Syllabus Ô94 A Higher Education Technology Conference August 14-17
University of CaliforniaÐSanta Cruz Santa Cruz, CA USA
 
Co-sponsored by Syllabus Press and Board of Education, UC-Santa Cruz Learn
the latest about new technology for higher education AND enjoy the
spectacular Monterey Bay region this August! 

Syllabus Ô94 is a conference for faculty, department chairs,
administrators, and technology staff who want to learn about the latest
technology for higher education. Professionals who work in technology and
textbook publishing companies are also invited to attend this conference.
In addition to the informative topical sessions, ample opportunities will
allow participants to interact with their colleagues from around the world
and learn more about issues relating to the use of technology in higher
education. 

The conference will be held at the University of California, Santa Cruz, a
campus of uncommon natural beauty, set in a Redwood forest overlooking
beautiful Monterey Bay and the Pacific Ocean. Numerous Òextra-conferenceÓ
activities are planned to take advantage of the location of this
summertime conference. 

Cross-platform and cross-technology:  All computer and technology
platforms will be covered, including DOS/Windows, Macintosh, and UNIX, as
well as multimedia, laser discs, presentation devices, quantitative tools
and other technologies. 

Cross-discipline focus:  The commonalities of technology use across
disciplines will be emphasized to stimulate participantsÕ thinking about
the use of technology in their respective fields. 

Pre-conference Workshops:  Sunday, August 13 will include a full day of
workshops providing detailed instruction and hands-on use of a variety of
technologies. 

Monday, Tuesday, and Wednesday Mornings:  A variety of plenary sessions
will be devoted to important higher education technologies, including
demonstrations. 

Monday, Tuesday, and Wednesday Afternoons:  Hands-on labs will give
participants an opportunity to explore the technology firsthortunity to
explore the technology firsthand; discussion groups will explore other
issues of concern to higher education professionals.  Tours and off-site
activities will allow participants to enjoy the Monterey Bay region. 

For conference fees and registration information, send an e-mail to: 
Syllabus@netcom.com and request a conference brochure. Registration is
available by phone at (800) 773-0670. 

-- 
                                             syllabus@netcom.com

From owner-structural-nmr@net.bio.net Wed Jul 20 23:00:00 1994
Path: biosci!ND.EDU!Michael.C.Mossing.1
From: Michael.C.Mossing.1@ND.EDU (Mike Mossing)
Newsgroups: bionet.structural-nmr
Subject: Postdoctoral Fellowship
Date: 21 Jul 1994 06:31:57 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 49
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Please post:

Walther Cancer Research Fellowship - University of Notre Dame

NMR STUDIES OF DNA BINDING PROTEINS

The ideal applicant is an experienced NMR spectroscopist who would like to
learn protein engineering and expression and/or the biophysical chemistry
of DNA recognition. Protein structure and DNA recognition studies are
ongoing using three systems:

        So, the product of the sine oculis gene, is a new neurogenic
        homeodomain protein from Drosophila which has recently been cloned in 
        Dr. O'Tousa's lab at Notre Dame.  We have overproduced and purified the
        63 amino acid homeodomain from E coli with ~20mg/l yield.

        Pbx1, is a human proto-oncogene with sequence similarity to So.  We are
        interested in identifying the structure and function of homologous
        sequences outside the classical homeodomain.

        Monomeric variants of the lambda Cro Repressor (Mossing and Sauer  -- 
        Science 250 1712 (1990)).  Assignments  are complete (including 15N)
        for two variants which differ in the sequence of an engineered beta
        hairpin.  Second generation structural and DNA-recognition variants are
        being constructed for protein stability and DNA complex studies.

The College of Science NMR facility has a Varian Unity 500 MHz spectrometer
and will install a 600 MHz UNITYplus instrument with triple resonance and
pulse field gradient capabilities within the month.  Two new UNITYplus 300
MHz spectrometers are also being installed.

Walther Cancer Research Fellowships provide salaries for 2 years  at
$30,000/ year, with additional allotments of $7,500/year for supplies and
$1,500/year for travel. 

Please contact Mike Mossing for more information. Interested applicants are
asked to submit a curriculum vitae and letters from three references by
Sept. 15, 1994 to: Dr. Joseph E. O'Tousa, Department of Biological
Sciences, University of Notre Dame, Notre Dame Indiana 46556. The
University of Notre Dame is an Affirmative Action/Equal Opportunity
Employer. 

Thanks,


Mike Mossing, Department of Biological Sciences,      Phone   219/631-8412
University of Notre Dame, Notre Dame, IN 46556-5645   fax     219/631-7413 
        


From owner-structural-nmr@net.bio.net Fri Jul 22 23:00:00 1994
Path: biosci!CHSGI.CHEM.LSU.EDU!maskos
From: maskos@CHSGI.CHEM.LSU.EDU (Karol Maskos)
Newsgroups: bionet.structural-nmr
Subject: (none)
Date: 23 Jul 1994 16:04:17 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 51
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9407232304.AA01410@chsgi.chem.lsu.edu>
NNTP-Posting-Host: net.bio.net

Dear Str-NMR readers:

I know its summer but anyway I will try to get some help.

INTRODUCTION:

             I am studying a short peptide (21 residues).
This peptide forms a multimeric species in solution. From
sedimentation studies I know its octamer. CD and NMR data
strongly suggest the existence of the alpha-helical structure
in solution. On the basis of the H-D exchange exps. I have
built a model of octamer - the bundle of 4 dimers. Each dimer
contains two antiparallel alpha-helical units (head-to-tail
arrangement). My model is based purely on the H-D exchange
data. No intermolecular NOEs have been used to construct
the model because I simply do not have them (I do not have
this molecule 15N- or 13C-labeled).
On the basis of the intramolecular NOEs and J coupling constants
(194 constraints), using DSPACE, I have calculated the structure
of the monomeric unit which is mostly alpha-helical except
the two first residues which are dangling.
So my next obvious step using DISCOVER would be to calculate
the structure of the octamer. However, ..... 

QUESTIONS:

         (1) Does anybody in this group have experience with
             the rMD calculations on the multimeric species
             of identical subunits (Simulated Annealing Protocol)?

         (2) How to keep (constrain) these subunits together
             not having any experimental NOEs?

         (3) How to deal with the so called hydrophobic
             interactions within the DISCOVER?

Any help would be appreciated.
Thanks in advance to everyone.


Karol Maskos


---------------------+----------------------------I
Dr. Karol Maskos     |  maskos@chsgi.chem.lsu.edu I
Dept. Biochemistry   I                            I
LSU                  |                            I 
Baton Rouge          |  Ph  (504) 388 2667        I
LA 70803             |  Fax (504) 388 5321        I
---------------------+----------------------------I     


From owner-structural-nmr@net.bio.net Fri Jul 22 23:00:00 1994
Path: biosci!PINES6.LJCRF.EDU!elya
From: elya@PINES6.LJCRF.EDU (Elya S. Kurktchi)
Newsgroups: bionet.structural-nmr
Subject: Felix Notes
Date: 23 Jul 1994 16:10:53 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 19
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9407232312.AA03753@pines6.ljcrf.edu>
NNTP-Posting-Host: net.bio.net


Hi,

Does anybody have any help notes on Felix that they would like to
share with me?  I will start to use Felix, but it would be
nice to have some notes handy to go through and see what can really
be done with Felix.

Thanks.

Elya.

------------------------------------------------------------------------------
| Elya S. Kurktchi                       La Jolla Cancer Research Foundation |
| Scientific Computing Specialist/DOSC   10901 North Torrey Pines Road       |
| Email: elya@ljcrf.edu                  La Jolla, California  92037  U.S.A. |
| Phone: (619) 455-6480 x422             Fax: (619) 453-2242                 |
------------------------------------------------------------------------------


From owner-structural-nmr@net.bio.net Sun Jul 24 23:00:00 1994
Path: biosci!LAPLACE.CSB.YALE.EDU!abonvin
From: abonvin@LAPLACE.CSB.YALE.EDU ("Alexandre Bonvin")
Newsgroups: bionet.structural-nmr
Subject: RE: modeling of helix bundles
Date: 25 Jul 1994 06:02:51 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 45
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9407251303.AA01492@laplace.csb.yale.edu>
NNTP-Posting-Host: net.bio.net

In answer to Karol Maskos request...

> ....
> QUESTIONS:
> 

>          (1) Does anybody in this group have experience with
>              the rMD calculations on the multimeric species
>              of identical subunits (Simulated Annealing Protocol)?
> 

>          (2) How to keep (constrain) these subunits together
>              not having any experimental NOEs?
> 

>          (3) How to deal with the so called hydrophobic
>              interactions within the DISCOVER?
> 

> 


You might check the following papers:

* Automated modeling of coiled coils: application to the GCN4 dimerization 

  region. 

  Nilges & Brunger (1991) Protein Engineering 4, 649-659.

* Successful prediction of the coiled coil geometry of the GCN4 leucine zipper
  domain by simulated annealing: comparison to the X-ray structure.
  Nilges & Brunger (1993). PROTEINS: Struct. Funct. & Genetics 15, 133-146.


Alexandre

===============================================================================
| Alexandre Bonvin PhD                | Phone: (203) 432-5066                 |	
| Dept. Mol. Biophys. & Biochemistry  | Fax:   (203) 432-6946                 |
| Yale University, 266 Whitney Avenue | Email: abonvin@laplace.csb.yale.edu   |	
| New Haven CT 06511, USA             |                                       |
===============================================================================



From owner-structural-nmr@net.bio.net Mon Jul 25 23:00:00 1994
Path: biosci!ND.EDU!Michael.C.Mossing.1
From: Michael.C.Mossing.1@ND.EDU (Mike Mossing)
Newsgroups: bionet.structural-nmr
Subject: NMR Specialist - Position Available
Date: 26 Jul 1994 07:10:49 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 21
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199407261410.HAA18730@net.bio.net>
NNTP-Posting-Host: net.bio.net

NMR Specialist:  The University of Notre Dame has an immediate opening for
an NMR Spectroscopist.  The spectroscopist will be one of two Faculty
Professionals who are responsible for setup, maintenance, operation and
scheduling of NMR instruments (600 MHz, 500 MHz, and three 300 MHz
instruments) for research and teaching.  Primary duties for the
spectroscopist will involve interaction with faculty, staff and students to
design and execute appropriate NMR applications in chemistry, biochemistry,
biology and other areas of the physical sciences, participation in proposal
development for instrumentation upgrades, and participation in
collaborative research and teaching efforts.  Establishment of an
independent research program is possible, although not required. 
Qualifications include a Ph.D. with extensive NMR experience.  Previous
experience with Varian Unity Plus systems and a proficient knowledge of
UNIX is preferred.  Salary will be commensurate with experience. 
Applicants should send, by September 1, a complete description of their NMR
experience, a resume, and arrange for three letters of recommendation to
Dr. Marvin J. Miller, Chairman, Search Committee, Department of Chemistry
and Biochemistry, University of Notre Dame, Notre Dame, IN 46556.  The
University of Notre Dame is an equal opportunity employer.



From owner-structural-nmr@net.bio.net Mon Jul 25 23:00:00 1994
Path: biosci!internet!biosci!not-for-mail
From: kristoff (David Kristofferson)
Newsgroups: bionet.structural-nmr
Subject: UNSUBSCRIBING, BIOSCI ARCHIVES, ADDRESS DATABASE & BIOSCI FAQ
Date: 26 Jul 1994 02:00:11 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 322
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <199407260900.CAA04909@net.bio.net>
NNTP-Posting-Host: net.bio.net


Four important items follow: How to cancel e-mail subscriptions to
BIOSCI newsgroups, BIOSCI archive searching, the BIOSCI FAQ, and the
BIOSCI User Address Directory form.  If you have not yet listed
yourself in our BIOSCI user directory, please take a few minutes to
complete and return the form below.  If your personal information has
changed since you listed yourself, please send us a complete new
updated form.  We can not make manual revisions to existing entries.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				biosci-help@net.bio.net



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> To add yourself to the database just point your
> gopher client at merlot.gdb.org and select the following:
> 
> -->  15. Searching For Biologists/
> 
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> 
>   -->  1.  Add (or Correct) Your Address to the BIOSCI User Address
> Data..
> 
> 
> And fill out the form.

or Rob Harper's gopher site in Europe as follows:

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> 
> The path to the questionare is as follows.
> 
>    ---> 10. Finnish EMBnet BioBox/
> 
>         ---> 8.  FAQ Files/
> 
>                               FAQ Files
> 
>       1.  EMBnet: Information.
>       2.  EMBnet: Internet resources guide.
>       3.  A Biologist's Guide to Internet Resources/
>       4.  All FAQs (Frequently Asked Questions) Searches and Archives/
>   --->5.  Bionauts Address Database (questionaire) <TEL>


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previously.

The comment: lines may be used for anything that you like but PLEASE
DO NOT DELETE THEM FROM THE FORM OR ALTER THEM.  One suggested use is
to list the names of the newsgroups in which you participate.  Please
use the MAILING LIST name (see below - the latest version of the list
can be requested from biosci@net.bio.net) instead of the USENET name
even if you don't participate by e-mail.  WAIS might get confused by
the periods in the USENET names.  This allows one to retrieve via WAIS
or waismail the list of participants in a particular group.

For example:

comment: ARABIDOPSIS PLANT-BIOLOGY BIONEWS

On the comment: lines
use these names below ---- NOT the USENET names below

MAILING LIST NAME          USENET Newsgroup Name
-----------------          ---------------------
ACEDB-SOFT                 bionet.software.acedb
AGEING                     bionet.molbio.ageing
AGROFORESTRY               bionet.agroforestry
ARABIDOPSIS                bionet.genome.arabidopsis
BIOFORUM                   bionet.general
BIO-INFORMATION-THEORY     bionet.info-theory
BIONAUTS                   bionet.users.addresses
BIONEWS                    bionet.announce
BIO-JOURNALS               bionet.journals.contents
BIO-MATRIX                 bionet.molbio.bio-matrix
BIOPHYSICAL-SOCIETY        bionet.prof-society.biophysics
BIOPHYSICS                 bionet.biophysics
BIO-SOFTWARE               bionet.software
BIOTHERMOKINETICS          bionet.metabolic-reg
CELL-BIOLOGY               bionet.cellbiol
CHLAMYDOMONAS              bionet.chlamydomonas
CHROMOSOMES                bionet.genome.chromosomes
COMPUTATIONAL-BIOLOGY      bionet.biology.computational
CYTONET                    bionet.cellbiol.cytonet
DROSOPHILA                 bionet.drosophila
EMBL-DATABANK              bionet.molbio.embldatabank
EMPLOYMENT                 bionet.jobs
GDB                        bionet.molbio.gdb
GENBANK-BB                 bionet.molbio.genbank
GENETIC-LINKAGE            bionet.molbio.gene-linkage
GRASSES-SCIENCE            bionet.biology.grasses
HIV-MOLECULAR-BIOLOGY      bionet.molbio.hiv
HUMAN-GENOME-PROGRAM       bionet.molbio.genome-program
IMMUNOLOGY                 bionet.immunology
INFO-GCG                   bionet.software.gcg
JOURNAL-NOTES              bionet.journals.note
METHODS-AND-REAGENTS       bionet.molbio.methds-reagnts
MOLECULAR-EVOLUTION        bionet.molbio.evolution
MYCOLOGY                   bionet.mycology
NEUROSCIENCE               bionet.neuroscience
N2-FIXATION                bionet.biology.n2-fixation
PARASITOLOGY               bionet.parasitology
PHOTOSYNTHESIS             bionet.photosynthesis
PLANT-BIOLOGY              bionet.plants
POPULATION-BIOLOGY         bionet.population-bio
PROTEIN-ANALYSIS           bionet.molbio.proteins
PROTEIN-CRYSTALLOGRAPHY    bionet.xtallography
PROTISTA                   bionet.protista
RAPD                       bionet.molbio.rapd
SCIENCE-RESOURCES          bionet.sci-resources
STRUCTURAL-NMR             bionet.structural-nmr
TROPICAL-BIOLOGY           bionet.biology.tropical
VIROLOGY                   bionet.virology
WOMEN-IN-BIOLOGY           bionet.women-in-bio
YEAST                      bionet.molbio.yeast

Listing newsgroups on the comment: line is optional, of course.

Thanks again for your cooperation!



--------------- please cut here and return portion below ---------------

New information or Update to old record (enter N or U): 
date (DD-MM-YY): 
first name: 
middle initial: 
family name: 
job title: 
e-mail address: 
e-mail network: 
phone number: 
FAX number: 
institution: 
address1: 
address2: 
address3: 
city: 
state/province: 
country: 
postal code: 
research interest: 
research interest: 
comment: 
comment: 
comment: 
comment: 
comment: 


From owner-structural-nmr@net.bio.net Tue Jul 26 23:00:00 1994
Path: biosci!agate!howland.reston.ans.net!EU.net!ub4b!idefix.CS.kuleuven.ac.be!infoserv.rug.ac.be!allserv!wvranken
From: wvranken@allserv.rug.ac.be (Wim Vranken)
Newsgroups: bionet.structural-nmr
Subject: Sequential alfa-alfa NOEs
Date: 27 Jul 1994 11:59:55 GMT
Organization: University of Ghent, Belgium
Lines: 20
Message-ID: <315i7r$cv0@infoserv.rug.ac.be>
NNTP-Posting-Host: allserv.rug.ac.be
X-Newsreader: TIN [version 1.2 PL2]

Hello,

I was wondering if any of you has ever seen an almost complete range of
sequential alfa-alfa contacts in NOESY spectra of peptides/proteins. The
reason for this does not seem to be spin diffusion, as the peaks show up
with the right sign in ROESY spectra and they're still visible in the
NOESY spectra with short mixing times (150ms for a 35 residue peptide).
The only other explanation I can think of is that cis/trans isomerism of
the peptide bond is involved, but that does not seem very plausible. We've
also been searching for possible conformations with trans peptide bonds in
which the two alfa's are (relatively) near, and the shortest distance
possible here is about 4.3 angstrom. Since it's a flexible molecule, maybe
turns are formed in which the two alfa's are close enough? We're a bit at 
a loss at this time, so we'd really appreciate any help!

Wim Vranken

Biomolecular NMR Unit
University of Gent
Belgium

From owner-structural-nmr@net.bio.net Wed Jul 27 23:00:00 1994
Newsgroups: bionet.structural-nmr
Path: biosci!agate!howland.reston.ans.net!pipex!uknet!festival!leeds.ac.uk!news
From: garyt@resumix.portal.com (Gary Thompson)
Subject: Re: Felix Notes
Message-ID: <1994Jul28.084838.14639@leeds.ac.uk>
Sender: news@leeds.ac.uk
Reply-To: garyt@resumix.portal.com
Organization: Resumix, Inc., Santa Clara, CA
Date: Thu, 28 Jul 1994 08:48:38 GMT
References: <9407232312.AA03753@pines6.ljcrf.edu>
Lines: 6

I also am interested in Felix is there a mailing list/ ftp site 


gary



From owner-structural-nmr@net.bio.net Sat Jul 30 23:00:00 1994
Path: biosci!BIOC01.UTHSCSA.EDU!raman
From: raman@BIOC01.UTHSCSA.EDU (C.S.RAMAN)
Newsgroups: bionet.structural-nmr
Subject: Advanced School of NMR in Biology and Medicine
Date: 30 Jul 1994 23:21:03 -0700
Organization: BIOSCI International Newsgroups for Molecular Biology
Lines: 62
Sender: daemon@net.bio.net
Distribution: world
Message-ID: <9407301517.AA27574@bioc01.uthscsa.edu>
NNTP-Posting-Host: net.bio.net

  
 Dear colleague,
  
 I would like to inform you that we are organizing an Advanced School on NMR
 in Biology and Medicine, under the auspices of ISMAR and sponsored by the 
 Italian group of Magnetic Resonances (GDRM). The School will be held in 
 Altavilla Milicia (Sicily) from the 21st to the 30rd of September 1994, and
 will be structured in lectures and seminars according to the following 
 preliminary programme:
  
 21-23/9: Biological macromolecules structure:
          M.J.A. de Bie (NL), R. Kaptein (NL), I. Pelczer (U.S.A.), 
          H. Ruterjans (Germany)
  
 24/9   : Membranes
          A. Pines (U.S.A.), J. Seelig (Switzerland)  
  
 25-26/9: Cells
          H. Degani (Israel), G. Navon (Israel),  
          R.G. Ratcliffe (U.K.), F. Seguin (France)
  
 27/9   : Tissue extracts, perfused organs
          J.D. Bell (U.K.), S. Cerdan (Spain), P. Cozzone (France), 
          R.A. Iles (U.K.)
  
 28-30/9: In vivo spectroscopy and functional imaging
          C. Boesh (Switzerland), A. Haase (Germany), M. Hajek (Czech), 
          R. Menon (U.S.A.), S. Ogawa (U.S.A.), B. Ross (U.S.A.)  
  
 Subscriptions will be limited to 80 participants, with the aim of suscitate
 as  much  as  possible  interdisciplinary  discussions  on  any  useful 
 application of NMR techniques to the solution of biological and medical 
 problems.
  
 Costs:
 Registration fee........................ Lit. 500.000
 Living expenses (full board per day).... Lit. 100.000
  
 In case you or any other colleague would be interested, please contact us at
 the following addresses:
  
 Prof. Filippo Conti                            Prof. Alberto Spisni
 Dipartimento di Chimica                        Istituto di Chimca Biologica
 Universita' "La Sapienza"                      Universita' di Parma
 P.le Aldo Moro, 5                              Via A. Gramsci, 14
 00185  Roma                                    43100  Parma
 Italy                                          Italy
 phone: ++39-6-4455278                          phone: ++39-521-290362
 fax: ++39-6-4455278                            fax: ++39-521-988952
 E-mail: Conti@vaxrma.sci.uniroma1.it           E-mail: Chibio@ipruniv
-- 
C.S.Raman                           
UNIX Programming & Administration   
SPARC & SGI Systems                 raman@bioc01.uthscsa.edu - INTERNET
Department of Biochemistry          raman@mintaka.chpc.utexas.edu - CHPC
UTHSCSA                             c.raman@launchpad.unc.edu
7703 Floyd Curl Dr.                 (210) 567-6623   [Tel]
San Antonio, TX 78284-7760          (210) 567-6595   [Fax]
******************************************************************************
         If a man's wit be wandering, let him study the Mathematics
                                                            -Francis Bacon   
******************************************************************************

