Greg Brown (greg at mynx.demon.co.uk) writes:
> I am currently studying what progress is being made in finding in
> vitro alternatives to current in vivo methods using animal models.
>> I would be very grateful if anyone with information or who is working
> in this field would email me.
>> I am particularly interested in any research into in vitro methods of
> irritancy and toxicological assement.
I see that you are posting from the UK. I would suggest you get in touch
with FRAME at the University of Nottingham. They publish a journal on
in vitro alternatives called ATLA. There's also the Center for
Alternatives at Johns Hopkins in the US. They publish a newsletter and
sponsor an annual meeting. The proceedings are published (there's at
least 7-8 volumes by now).
With respect to skin irritation testing alternatives, here in Canada Dr.
Dan Sauder's group at Univ. of Toronto have been working on a biossay
method with cultured human epidermal keratinocytes for several years.
--
Lawrence Segal
Ottawa, Ontario, CANADA
