Physiology of mouse is not well studied because of the lack of
device to measure physiological parameters. Cardiac output is one
of the important parameters in assessing cardiovascular
parameters in response to drug. In addition, the effect of
different gene expression related to cardiovascular abnormalities
can be carried out in transgenic mice. We have measured cardiac
output in mice by following thermodilution technique using
cardiac output computer. The computer can measure heart rate,
blood pressure and stroke volume and cardiac output
simultaneously. In order to get the cardiac output, scientists
need to put catheter in jugular vein and temperature probe in
carotid artery in anesthetized mice. In order to get blood
pressure, they need to catheterize femoral artery. If you need
more information, please provide your street address, I will mail
you all necessary information.
PKG
Internet: 75144.2413 at compuserve.com
