Radiolabelled TCDD

T. Scott Thurmond thurmons at EHSCT7.ENVMED.ROCHESTER.EDU
Tue Jul 30 11:24:28 EST 1996

Simon Cowell wrote:
> I was hoping to get some help from someone out there.  I am
> expressing the aryl hydrocarbon (Dioxin) receptor in insect
> cells and want to study its binding to a number of known
> ligands and potential ligands in complex mixtures.  To check
> the activity of the expressed protein through the Ni-NTA
> purification scheme I was hoping to use radiolabelled TCDD.
> However, I am having extreme difficulty obtaining any.  I would
> prefer to work with tritiated or 14-C labelled 2,3,7,8-TCDD
> rather than radioiodinate as some labs do.  Can anyone help me
> get a hold of some ?
   Try Cambridge Isotope Laboratories, 50 Frontage Rd., Andover, MA 
01810-5413, Canada 800 no., 1-800-643-7239, Fax. 1-508-749-2768
Good luck.

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