CYP7B in hippocampus

Christopher Hatton Hatton at ifn-magdeburg.de
Wed Apr 2 04:18:45 EST 1997

Eva wrote:
> Hi all,
> I bumped into your conversation about CYP7B, which I find very interesting,
> as it is one
> of the few P450s that are most abundantly expressed in the brain (and not
> in the liver).
> As it is, I have one question, that is if CYP7B is known to be able to
> hydroxylate cholesterole (like CYP7A), and if so, is it to such an extent
> that it
> would be of any physiological role.
> Thankful for an answer
> Eva
> Eva Hedlund
> Dept. of Medical Nutrition
> Karolinska Institute
> F60 Novum
> Huddinge, Sweden

Eva, this is my question also, I'm wondering if its involved in
corticosteroid control which might also be of interest to nutrionlists,
but also possible a possible neuroprotective affect against Ischaemia. 
However I keep drawing blanks, it seems that this and other newsgroups
don't have the readers we need to answer our questions.

(ofcourse anyone wishing to comment or throw in a hypothesis is more
than welcome)

Christopher Hatton
BL- Institut für Neurobiologie
Abteilung Neurophysiologie
PSF 1860
D-39008 Magdeburg
TO AVOID SPAM PLEASE EMAIL ME at this address:-  Hatton at ifn-magdeburg.de
Is life just a game where we make up the rules while we're searching for
something to say,
or are we just simply spiralling coils, Of self replicating DNA.  FROM
Monty Pythons "The meaning of Life"

Please note that these are my own views and not those of the IfN., 
Http://www.ifn-magdeburg.de    (in English and German)

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