Hello,
Some time ago we published some papers relating to cytochrome
P450 proteins and their activities. We would be very grateful for
any information as to whether any of the work noted below has been
followed up and for any relevant references (esp. in conference
proceedings, books etc.).
The publications concerned were:
1) R.H.Wickramasinghe, " Regulation of corticosteroid
hydroxylations: the intramitochondrial dielectric constant and
proteolipids of adrenodoxin and cytochrome P450 ", CYTOBIOS
(Cambridge, England) 8(1973)81-94,
2) R.H.Wickramasinghe, " The regulation of corticosteroid
hydroxylations. 1. An effect of inorganic ions in regulating iron-
sulphur protein-dependent electron transport ", JOURNAL OF
BIOENERGETICS 5(1973)151-161,
3) R.H.Wickramasinghe and C.A.Villee, " Early role during chemical
evolution for cytochrome P450 in oxygen detoxification ", NATURE
256(1975)509-511,
4) R.H.Wickramasinghe and C.A.Villee, " Possible similar role of
cytochrome P450 in primordial evolution of species and in chemical
carcinogenesis " , PERSPECTIVES IN BIOLOGY AND MEDICINE
19(1976)473-475,
5) R.H.Wickramasinghe, " Dielectric constants and lithium ion
treatment of psychiatric illness ", Abstracts, 35th Annual National
Meeting of the American Federation for Clinical Research, 30 April
- 1 May 1978 at San Francisco, California, CLINICAL RESEARCH
26(1978)297A,
6) R.H.Wickramasinghe, G.Mueller and K.Norpoth," Spectral evidence of
interaction of spice constituents with hepatic microsomal
cytochrome P-450 ", CYTOBIOS (Cambridge, England) 29(1980)25-27,
7) R.H.Wickramasinghe, " The effects of glutathione on the
11beta-hydroxylation of 11-deoxycorticosterone by bovine adrenal
cortex mitochondria ", BULLETIN OF ENVIRONMENTAL CONTAMINATION
AND TOXICOLOGY 12(1974)99-103,
8) R.H.Wickramasinghe and G.T.Bryan, " Effect of progesterone on
human corticosteroid 21-hydroxylation ", EXPERIENTIA
31(1975)1366-1367.
Thank you very much for taking the time to read this and in advance
for any help you can give.
Regards,
Rohan H. Wickramasinghe
