IUBio

IC HAS A CHANCE NNnnnaaaaaaaa....

Ken Gates kgates at jnpcs.com
Sun Sep 14 21:52:05 EST 1997


Here is another study done by Ruth Kriz and Anne Peck, Now I know Ruth but
have not had the pleasure of meeting Anne. This study was done to see if
antibiotics would cure IC.
There were some good results found. One of which is the long term use of
antibiotics CAN help in the symptoms of IC and the possibility of cure.

Remember YOU Must consult you DR before before doing antibiotics.
Ruth Kriz and Anne Peck are not offering any medical advice.
This document is being published to offer IC suffers different ways that IC
can be helped.
Ken Gates kgates at jnpcs.com

Study to Evaluate
Antibiotic Treatment for IC
Ruth Kriz, R N & Anne Peck

( In 1990. the ICA awarded a pilot research grant to Ruth Kriz, R.N.,
M.S.N., C.P.N.P. and Anne W. Peck for their project "The Evaluation of
Antibiotic Therapy Recommended by Dr. Paul Fugazzotto for the Treatment of
IC.' Ms. Kriz Was the  ICA State Coordinator for Virginia. Below are the
results of her study.

( Ms. Kriz undertook this study to evaluate the efficacy of long-term
antibiotic therapy in the treatment of IC based on the findings of South
Dakota microbiologist. Paul Fugazzotto, Ph.D. For five years, Dr. Fugazzott,
using a washing procedure and broth culture media has reported culturing
gram positive bacteria (primarily enterococcus and gaffkya) in the urine of
over 95% of IC patients he has examined. It is the belief of Dr. Fugazzott
that IC is caused by an infection in the wall of the bladder and can be
treated by antibiotic use.

( In the Kriz/Peck study, 100 patients were surveyed whom reported positive
urine cultures from Dr. Fugazzotto's laboratory. Analysis was based on 62
Patients who had tried antibiotics ranging from 2-14 months. The 62
respondents were divided into 3 groups:


 1)   IC diagnosis confirmed by a physician based on NIH.

2)  1C diagnosis suspected but test results either not obtained or
inconclusive. (9 patients)

3)  Positive IC diagnosis reported by patient but physician did not respond
to letter requesting confirmation. (15 patients)
      Of the 3 groups statistical analysis revealed no differences between
the groups on any of the variables.

* Two rating scales were used. One rated frequency of symptoms ranging from
"never" to "daily". The second scale rated severity of symptoms including
pain, pressure, urgency, and frequency and burning. This scale ranged from
"no discomfort at all" to "very severe discomfort." The severity and
frequency of symptoms were then graphed for (1) the time before antibiotics
were administered (2) while the antibiotics were administered and (3) after
the antibiotic were discontinued. The graphs below illustrate the marked
improvement in severity and frequency of symptoms while antibiotics were
taken and after they were discontinued these graphs represent an average
improvement. Some patients had slight improvement while others experienced
dramatic improvement of their IC symptom.


(GRAPH WOULD NOT POST IN TEXT ) If you would like a copy of the in tire
document in word7
E-mail me
kgates at jnpcs.com


* Out of 16 respondents who reported duration, the average time on
antibiotics was 5.7 weeks. Thirty-four stopped the medication; 26 were
continuing at the time of the survey. Those continuing reported even further
improvement in their
symptoms than the 34 who stopped. Reasons for discontinuing antibiotics
included side effects (17), doctor
recommended (14), no improvement (13) and other reasons (4).

Seventy-nine percent of IC patients surveyed reported the use of long term
antibiotics improved their symptoms.     Statistically significant
differences were found in severity of symptoms and their frequency both
during and after antibiotics were taken when compared with prior symptoms.
Those who continued on the antibiotics reported greater improvement than
those who stopped.

* While these preliminary results appear promising, it is important to note
that a larger sample size and a double-blind placebo clinical trial would be
necessary to further substantiate these findings. If you are considering
trying antibiotic theory it is important that you consult you physician. In
addition, patients on antibiotics need information on bowel bacteria
replacement, which may prevent diarrhea as well as ways of preventing yeast.










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