> From: Dr.R.S.Rao <rsrao at blr.vsnl.net.in>
> To: toxicology <toxicol at net.bio.net.>
> Subject: wish to subscribe, to receive e-mail of discussion group.
> Date: 23 January 1999 16:39
>> I wish to subscribe, to receive e-mail of discussion group.
>> I have a query regarding, formulating compounds, to carry out acute and
> subacute toxicity studies,through parenteral
> route,particularly,I.V route,in rodents.
>> I wish to know what are the common vehicles and solvent used,for
> route of administration(I.V and I.P)? What is the
> concentration and total amount of these can be administered,without
> side effects? In order to achieve the high
> concentration required,especially to carryout acute studies,(particularly
> the compounds which are not water soluable)what
> procedures to be adapted?
>> I shall be thankful.if any one could help me in these aspects.