Not acetaminophen but one of its metabolites is responsible for the
lipid peroxidation. To test this your testsysteem should be able to form
this metabolite.
papakos at ibm.net wrote:
>> Does anybody know what lipid changes acetaminophen induces
> in liver or kidneys?
> I have read that APAP augments lipid peroxidation at concentrations:
> 0.5 to 5.0 mM BUT
> when i tested the compound i found no lipid peroxides usind 1 mM within 5
> hours incubation time?
> Any suggestions?
>> A Scientist
--
Dr.Ir. Chris T.A. Evelo PhD
Department of Pharmacology & Toxicology; Universiteit Maastricht
P.O. Box 616; NL-6200 MD Maastricht; The Netherlands
tel: +31-43-3881231 +31-43-3881417; fax: +31-43-3670940
email: C.Evelo at Farmaco.UniMaas.nl
