Toxicological aspects of chewing gum

Charles Miller rellim at tulane.edu
Wed Nov 28 10:13:55 EST 2001

Xylitol is a common additive in foods and is a normal metabolite derived
from glucose. Butylated hydroxyanisole (BHA) is an antioxidant that is
commonly added to foods. Both are generally recognized as safe in the
amounts typically found in foods and chewing gums. Titanium dioxide is a
white compound that is generally inert. It is of concern when respired in a
particulate form (mainly by people with high exposure in industrial
settings). In this instance it causes lung damage by a mechanism that
involves free-radical production, similar to silica and other inhaled
particulate matter.

These compounds have a long history of use by large numbers of people and
they appear to be safe. I am not aware of any adverse interactions between
these compounds.


Chuck Miller


Charles A. Miller, III, Ph.D.
Associate Professor of Environmental Health Sciences
Tulane University School of Public Health and Tropical Medicine
1430 Tulane Ave.
New Orleans, LA 70112
(504)585-6942    rellim at tulane.edu
Bionet.toxicology news group: http://www.bio.net/hypermail/toxicol/current



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