Unnatural Ageing

Tony Weiss weiss at ee.su.oz.au
Thu Aug 29 20:49:16 EST 1991

Ricardo Negrete writes:
I saw a program once in PBS about a starnge genetic disoder.
This disease cause children to age unnaturally quickly.
By time a child reached the age of six his/hesr body was
like that of a 60 year old person.

Can anyone tell me the name of this genetic disoder?

Any bibliographic information would also be appreciated.

Thanks in advance.
Ricardo Negrete               rnegrete at digi.lonestar.org

The disease is probably Hutchinson-Gilford progeria. Affected
kids show many (but not all) the apparent features of aged people
and usually suffer from severe cardiovascular problems. They often
die by their early teens.

You asked for a couple of references. As a start, try:

Mills, R.G. and Weiss, A.S. (1990) Gerontology 36:84-98

de Busk, F.L. (1972) J. Pediatr. 80:697 -724.

We published the first of these. Ted Brown has also written some
nice reviews in the area, and there are some other good ones too
which will take too much space to list.

Hope this has been of help.

Tony Weiss
weiss at ee.su.oz.au
Dept Biochemistry  G08
University of Sydney 
NSW  2006

"usual disclaimers apply"

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