Telomeric Theory - Implications

Excelife excelife at earthlink.net
Sat Nov 7 19:27:33 EST 1998

In article <3646af15.6416477 at nntp.ix.netcom.com>, stollman at neverspam.com  
>Yesterday, the chief scientist of Geron was on PBS TV news, talking
>about Geron Research into immortality of human cells. Geron has a  pile
>of patents, they spent millions of Dollars on research in the past
>decade. Yet, they do not have a single drug, or any other product in
>pharmacies that a doctor could prescribe to an elderly patent.  It is
>highly unlikely that they will have any such product in the foreseeable
>future, as theGeron's CSO said  that it still will take at least 10 more
>years to have anything useful.  One has to wonder if they are not the
>20th century equivalent of 19th century snake oil cures. Especially
>since you do not hear any confirmation from the big drug companies of
>anything that Geron does. And the big drug companies are not timid in
>issuing press releases.

Your analysis is in-consistent and underscores the differences between 
legitimate scientific investigations into aging and the "snake oils" you 
complain about.

If Geron were pushing some drug or supplement and basing claims on some 
obscure research study or even worse, testimonials, then you might have a 
legitimate complaint.

Instead they are conducting studies with some of the most prestigious 
laboratories in the world including Sloan Kettering and Cold Harbor.  If you 
check some of the references in my article or in Medline you will see that 
the research is being conducted worldwide and an understanding of how 
telomeres are involved in aging is coming into focus.

But it is *research* and the fundamental processes have to be delineated 
before any therapy can be developed. That Geron might have some some product 
available in just ten years is actually very encouraging.  The "normal" 
development time of a drug from research thru clinical trials to FDA approval 
is usually quite longer.

That you haven't heard anything from other drug or pharmaceutical companies 
is not surprising.  They usually don't get involved in a product until it is 
approaching clinical trials and those they publicize thoroughly.  Their 
involvement in basic research is far more surreptitious.  They don't publish 
or announce their findings until they have the processes firmly secured by 
patents.  Perhaps that's one of the reasons Geron is able to go on PBS while 
most other companies are "hiding" their research.

I'm just glad that the research is proceeding and Lifeline Labs. will do its 
part in supporting these studies.

Thomas Mahoney, Pres.
Lifeline Laboratories, Inc.

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