Anti-Aging Science

Leonid Gavrilov lagavril at midway.uchicago.edu
Fri Mar 1 17:09:51 EST 2002

Dear Colleagues,

I thought that perhaps this scientific community may be interested to know 
about the existence of  legitimate anti-aging studies published in 
reputable scientific journals by established researchers.

Here is a sample example of such studies (21 references). The terms like 
'anti-aging' in the titles of the publications are highlighted in CAPITAL 

Cavallini G, Donati A, Gori Z, Pollera M, Bergamini E. The protection of 
rat liver autophagic proteolysis from the age-related decline co-varies 
with the duration of ANTI-AGEING food restriction. Exp Gerontol 2001 

Hipkiss AR. Carnosine, a protective, ANTI-AGEING peptide? Int J Biochem 
Cell Biol 1998 30(8):863-8

Hipkiss AR, Brownson C. A possible new role for the ANTI-AGEING peptide 
carnosine. Cell Mol Life Sci 2000 57(5):747-53

Hipkiss AR, Brownson C. Carnosine reacts with protein carbonyl groups: 
another possible role for the ANTI-AGEING peptide? Biogerontology 

Hipkiss AR, Brownson C, Carrier MJ. Carnosine, the ANTI-AGEING, 
anti-oxidant dipeptide, may react with protein carbonyl groups. Mech Ageing 
Dev 2001 122(13):1431-45

Knook DL. ANTIAGING strategies. Ann. N. Y. Acad. Sci. 1992 663:372-5.

Lane MA, Baer DJ, Rumpler WV, Weindruch R, Ingram DK, Tilmont EM, Cutler 
RG, Roth GS Calorie restriction lowers body temperature in rhesus monkeys, 
consistent with a postulated ANTI-AGING mechanism in rodents. Proceedings 
of the National Academy of Sciences of the United States of America 1996 93 
(9): 4159-4164

Masoro EJ. Potential role of the modulation of fuel use in the ANTIAGING 
action of dietary restriction. Ann N Y Acad Sci 1992 663:403-11

Masoro EJ. ANTIAGING action of caloric restriction: endocrine and metabolic 
aspects. Obes Res 1995 3 Suppl 2:241s-247s

Masoro EJ. Possible mechanisms underlying the ANTIAGING actions of caloric 
restriction. Toxicol Pathol 1996 24(6):738-41

Masoro EJ. Hormesis and the ANTIAGING action of dietary restriction. Exp 
Gerontol 1998 33(1-2):61-6

Masoro EJ, Austad SN. The evolution of the ANTIAGING action of dietary 
restriction: a hypothesis. J Gerontol A Biol Sci Med Sci 1996 51(6):B387-91

Meites J. ANTI-AGEING interventions and their neuroendocrine aspects in 
mammals. J. Reprod. Fertil., Suppl 1993;46:1-9.

Moriguchi T, Saito H, Nishiyama N. ANTI-AGEING effect of aged garlic 
extract in the inbred brain atrophy mouse model. Clin. Exp. Pharmacol. 
Physiol. 1997 24(3-4):235-42

Norris CM, Halpain S, Foster TC. REVERSAL of age-related alterations in 
synaptic plasticity by blockade of L-type Ca2+ channels. J. Neurosci. 

Novelli M, Masiello P, Bombara M, Bergamini E. Protein glycation in the 
aging male Sprague-Dawley rat: effects of ANTIAGING diet restrictions. J 
Gerontol A Biol Sci Med Sci 1998 53(2):B94-101

Rattan SI. The nature of gerontogenes and vitagenes. ANTIAGING effects of 
repeated heat shock on human fibroblasts. Ann N Y Acad Sci 1998 854:54-60

Shimokawa I, Higami Y. A role for leptin in the ANTIAGING action of dietary 
restriction: a hypothesis. Aging (Milano) 1999 11(6):380-2.

Svendsen L, Rattan SI, Clark BF. Testing garlic for possible ANTI-AGING 
effects on long-term growth characteristics, morphology and macromolecular 
synthesis of human fibroblasts in culture. Ethnopharmacol 1994 43(2):125-33

Yu BP Approaches to ANTI-AGING intervention: the promises and the 
uncertainties. Mech Ageing Dev 1999 111 (2-3): 73-87

Van Remmen H, Guo Z, Richardson A. The ANTI-AGING action of dietary 
restriction. Novartis Found Symp 2001;235:221-30

For more information visit the following website:

Dr. Leonid A. Gavrilov, Center on Aging
NORC/University of Chicago
1155 East 60th Street
Chicago, IL 60637-2745
Fax: (773) 256-6313, Phone: (773) 256-6359


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