University of Missouri
University of Georgia
Postdoctorals in Physical and Genetic Mapping
Postdoctorals in Bioinformatics
Research Technicians; Systems Analyst; Programmer Personnel
A collaborative Project on physical, genetic, and bioinformatics
resources for maize is being inaugurated by the University of Missouri,
Clemson University, and the University of Georgia. The long-term goals
of the Project are: 1) to create a physical map of maize anchored to the
genetic map by screening and assembling bacterial artificial chromosome
(BAC) clones, and 2) to design and augment informatics and database
capabilities to collect, analyze, and disseminate the data publicly.
Because this is a substantial resource- and tool-development project
with high potential impact, interactions and cooperation with diverse
plant scientists are anticipated. We are seeking skilled, enthusiastic,
and innovative participants for the research program.
-- PROJECT MANAGER --
MAIZE GENOMICS CENTER
A Ph.D. scientist experienced in genetics and related sciences is needed
to provide administrative oversight for the inaugural Project of the new
Maize Genomics Center at the University of Missouri. The Project focuses
on developing physical, genetic, and bioinformatics resources for the
maize genome. The research will be conducted by scientists at the
University of Missouri, Clemson University and the University of
Georgia. The PROJECT MANAGER will report to the Director of the Center
and will be responsible for developing a detailed understanding of all
scientific aspects of the project; for facilitating communication among
participants, both on-campus and at collaborating sites; and for
responding to inquiries or requests from government agencies, University
offices, visitors, and the press. Qualified individuals are expected to
have excellent interpersonal skills and demonstrated experience in
monitoring progress of projects; writing grants and reports; devising
presentation materials; managing budgets; and handling recruiting and
personnel matters. Applicants should mail a cover letter, curriculum
vitae containing complete record of training and experience, and names
of three references to Dr. E.H. Coe, Director, Maize Genomics Center,
210 Curtis Hall, University of Missouri, Columbia, MO 65211-7020.
-- Postdoctoral Research Associates --
PHYSICAL AND GENETIC MAPPING
o To map RFLPs onto reference genetic populations and to anchor BACs to
genetic map. Requires experience in probing filter arrays and analyzing
o To develop and map SSR markers and to use them to anchor BACs.
Requires expertise in sequencing; primer development; DNA sequence
search routines; PCR; and analyzing high-density genetic mapping data,
preferably in a high-throughput environment.
o To map expressed sequence tags (ESTs) to BACs. Requires experience
in probing filter arrays and analyzing data, preferably in a
o To develop methods for making and mapping in whole-genome radiation
hybrids. Requires experience with tissue culture (plant or animal), and
collection and analysis of mapping data, preferably as applied to
radiation hybrids in a high-throughput environment.
o To devise descriptors for expressions, development, and responses to
describe plant traits systematically for the Maize Genome Database.
Requires expertise in botanical / agricultural / biological concepts,
preferably with background in database construction and manipulation.
--Applicants for the above postdoctoral positions at Missouri should
mail CV and selected reprints, plus phone and email addresses of at
least 3 references, to: Dr. E. H. Coe, Director, Maize Genomics Center,
210 Curtis Hall, University of Missouri, Columbia, MO 65211-7020. Email
or incomplete applications cannot be considered.
o To play a central role in assembly of comparative physical maps of
maize, sorghum, rice, and other grasses, by hybridization of mapped DNA
probes to BAC grids. Familiarity with plant genetics and BAC
manipulations important, familiarity with robotics and databases a plus.
--Applicants for the above postdoctoral position at Georgia should
submit CV, selected reprints, plus phone and email addresses of at least
3 professional references to: Dr. Andrew H. Paterson, c/o Office of the
Vice-President for Research, University of Georgia, Athens GA 30602, or
by email to htucker at arches.uga.edu.
o To construct positional cloning and sequence ready physical maps.
Coordinate a team to fingerprint a 200,000-clone BAC library and to
assemble and annotate contigs using anchor data and IMAGE and FPC
software. Extensive experience in contig assembly and UNIX programming
required. Salary commensurate with experience.
--Applicants for the above postdoctoral position at Clemson should send
CV, publications, and three letters of recommendation by email to Rod
Wing, rwing at clemson.edu, or Ralph Dean, rdean at clemson.edu.
-- Postdoctoral Research Associates --
o To develop software for managing data within the project, porting data
from lab databases to the Maize Genome Database, and disseminating
mapping data. Requires appropriate expertise and ability to interact
effectively with collaborating scientists, preferably aided by
o To devise computational tools for analyzing data generated from RFLP
mapping, BAC mapping, and radiation hybrid projects. Requires
experience in data analysis, combined background in biology and computer
o To coordinate and participate in database development for porting
laboratory-generated data to other databases; for graphical map viewing;
for a facile table-making tool; for automated progress reports and www
pages defined by the research groups and outside reviewers as needed for
the community. Requires experience with diverse database types and data
delivery, biology a plus.
--Applicants for postdoctoral positions in bioinformatics at Missouri
should mail complete resume to: Dr. E. H. Coe, as above.
-- Research Technicians --
o To develop and map SSR markers and to use them to screen BACs.
Requires B.S. or M.S., advanced molecular biology skills, and experience
with spreadsheet software.
o To sequence clones for development of SSR markers to be used in
genetic and physical mapping. Requires B.S. or M.S., advanced molecular
biology skills, and experience with automated sequencing and associated
o To screen BAC filter arrays or DNA pools with EST clones. Requires
B.S. or M.S., advanced molecular biology skills, and experience with
filter hybridization and PCR.
o To map RFLPs, SSRs and ESTs on radiation hybrid panel. Requires B.S.
or M.S., advanced molecular biology skills, and experience with filter
hybridization and PCR.
-- Systems Analyst ?
o To maintain server functions integral to data management between
collaborators in the Project. Requires experience in establishing and
maintaining NT networks and in managing relational databases.
-- Computer Programmers ?
o To handle data, write scripts, assist compiling and porting data from
genetic and physical mapping. Requires B.S. in computer science or
related area; C, JAVA, PERL; background in biology a plus.
o To revise existing software for handling and analyzing data generated
from the mapping projects. Requires B.S. in computer science or related
area and experience with relevant software; C, JAVA, PERL; background in
biology a plus.
Applicants should specify the technical position for which application
is being made, and mail complete resume, including relevant experience,
skills, and phone and email addresses of three references to: Dr. E. H.
Coe, Director, Maize Genomics Center, 210 Curtis Hall, University of
Missouri, Columbia, MO 65211-7020.
The University of Missouri, Clemson University, and the University of
Georgia are Equal Opportunity, Affirmative Action employers.