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[Arabidopsis] Postdoc Position, Versailles, France

Hakim MIREAU via arab-gen%40net.bio.net (by Hakim.Mireau from versailles.inra.fr)
Wed May 2 02:09:51 EST 2007

Postdoctoral Position
INRA, Versailles, France

A 2-year postdoctoral research position is available starting September 
2007 to study the molecular mechanisms of fertility restoration in the 
Ogura cytoplasmic male sterility (CMS) system. CMS is a maternally 
inherited trait in higher plants that prevents the production of 
functional pollen. The Ogura CMS, initially found in radish and later 
transferred to rapeseed, is controlled by the expression of the orf138 
mitochondrial locus. The expression of orf138 can be suppressed by the 
Rfo gene product, whose presence in the nuclear genome restores male 
fertility. The Rfo gene was recently cloned and revealed to code for a 
PentratricoPeptide Repeats protein. The position will concern the 
biochemical characterization of the restorer protein to better 
understand the mechanisms by which Rfo prevents the synthesis of ORF138. 
PPR repeat containing proteins have been found to be major players in 
organelle gene expression and were shown to be involved in various 
aspects of RNA processing. By extension, the characterization of Rfo 
will provide key elements to better understand the molecular activities 
of this exciting protein family, especially the way they functionally 
interact with specific RNA targets.
Candidate will work at the Versailles Center of the National Institute 
for Agronomical Research (INRA), which possesses state-of-the-art 
research equipments, and facilities devoted to post-genomic 
technologies, including cell imaging, functional proteomics, transgenic 
plants etc…
Candidates with strong background in biochemistry/molecular biology and 
related research experience are especially encouraged to apply. 
Extensive experience with RNA purification will be an advantage. Salary 
will be commensurate with experience. To be eligible, candidates should 
not be French. To apply, send resume and a cover letter describing your 
interests, as well as names and contact information of two references to 
mireau from versailles.inra.fr
Web sites for more information:

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