[Bio-software] UniProt Release 8.0 Note

Raja Mazumder rm285 at georgetown.edu
Thu Jun 1 12:56:52 EST 2006


Dear Subscriber,

********************************************************************************
			UniProt Release 8.0 Note
				30-May-2006
********************************************************************************


CONTENTS
1. Introduction
2. Database description
3. Current release contents
4. Description of changes made to UniProt since release 7.0
5. Forthcoming changes
6. How to link to UniProt
7. Feedback
8. Acknowledgements
9. Terms of use
10. Citation
11. Contact

1. INTRODUCTION
The UniProt Consortium--European Bioinformatics Institute (EBI), Swiss 
Institute of Bioinformatics (SIB) and Protein Information Resource 
(PIR)--is pleased to announce UniProt Release 8.0 (30-May-2006). UniProt 
is updated bi-weekly, and can be accessed online for searches or 
download at http://www.uniprot.org.

2. DATABASE DESCRIPTION
UniProt is a centralized resource for protein sequences and functional 
information. UniProt was created by joining together the information 
from Swiss-Prot, TrEMBL and PIR. UniProt is comprised of three 
components, each optimized for different uses: a) UniProt Knowledgebase 
(UniProtKB), b) UniProt UniProt Reference Clusters (UniRef), and c) 
UniProt Archive (UniParc). Additional information on UniProt is 
available at http://www.uniprot.org/database/DBDescription.shtml and in 
the UniProt Knowledgebase user manual 
(http://expasy.org/sprot/userman.html).

3. CURRENT RELEASE CONTENTS
-------------------------------------------------------------
UniProt Release 8.0
-------------------------------------------------------------
Database -- Entries
-------------------------------------------------------------
UniProtKB -- 3,170,612 (UniProtKB/Swiss-Prot section: 222,289; 
UniProtKB/TrEMBL section: 2,948,323)
UniRef100 -- 3,511,676
UniRef90 -- 2,254,474
UniRef50 -- 1,148,123
UniParc -- 7,116,519
-------------------------------------------------------------
Detailed release statistics for UniProtKB/Swiss-Prot and 
UniProtKB/TrEMBL sections of the UniProt Knowledgebase can be viewed at 
http://www.expasy.org/sprot/relnotes/relstat.html and 
http://www.ebi.ac.uk/swissprot/sptr_stats/index.html, respectively.

4. DESCRIPTION OF CHANGES MADE TO UNIPROT SINCE RELEASE 7.0
UniProt Knowledgebase - To learn about the changes since the last major 
release please read the UniProtKB/Swiss-Prot and UniProtKB/TrEMBL 
release notes (http://expasy.org/sprot/relnotes/) and the recent changes 
document (http://expasy.org/sprot/relnotes/sp_news.html).

5. FORTHCOMING CHANGES
Forthcoming changes concerning the UniProt Knowledgebase are described 
in http://expasy.org/sprot/relnotes/sp_soon.html.

6. HOW TO LINK TO UNIPROT ENTRIES
How to link to UniProt entries can be found at 
http://www.uniprot.org/support/docs/linkUniProt.html

7. FEEDBACK
We are constantly trying to improve our database in terms of accuracy 
and representation and hence, consider your feedback extremely valuable. 
Please contact us if you have any questions 
(http://www.uniprot.org/support/helpdesk.shtml) or comments 
(http://www.uniprot.org/support/feedback.shtml). You can also subscribe 
to e-mail alerts (http://www.uniprot.org/support/alerts.shtml) for the 
latest information on UniProt databases.

Submit new sequence data, updates and corrections at 
http://www.uniprot.org/support/submissions.shtml

8. ACKNOWLEDGEMENTS
UniProt is mainly supported by the National Institutes of Health (NIH) 
grant 1 U01 HG02712-01. Additional support for the EBI’s involvement in 
UniProt comes from the two European Union contracts BioBabel 
(QLRT-2000-00981) and TEMBLOR (QLRI-2001-00015) and from the NIH grant 
1R01HGO2273-01. UniProtKB/Swiss-Prot activities at the SIB are supported 
by the Swiss Federal Government through the Federal Office of Education 
and Science. PIR activities are also supported by the NIH grants for 
NIAID proteomic resource (HHSN266200400061C) and grid enablement 
(NCI-caBIGICR-10-10-01) and National Science Foundation grants for 
iProClass (DBI-0138188) and BioThesaurus (ITR-0205470).

9. TERMS OF USE
UniProt is available for both commercial and non-commercial use. Please 
see http://www.uniprot.org/terms for details.

10. CITATION
If you want to cite UniProt in a publication please use the following 
reference:
Wu CH, Apweiler R, Bairoch A, Natale DA, Barker WC, Boeckmann B, Ferro 
S, Gasteiger E, Huang H, Lopez R, Magrane M, Martin MJ, Mazumder R, 
O'Donovan C, Redaschi N, Suzek B.  The Universal Protein Resource 
(UniProt): an expanding universe of protein information. Nucleic Acids 
Res. 2006 Jan 1;34(Database issue):D187-91.

11. CONTACT
EMBL Outstation
European Bioinformatics Institute (EBI)
Wellcome Trust Genome Campus
Hinxton
Cambridge CB10 1SD
United Kingdom
Telephone: (+44 1223) 494 444
Fax: (+44 1223) 494 468
Electronic mail address: datalib at ebi.ac.uk / swissprot at ebi.ac.uk
WWW server: http://www.ebi.ac.uk/

Swiss Institute of Bioinformatics (SIB)
Centre Medical Universitaire
1, rue Michel Servet
1211 Geneva 4
Switzerland
Telephone: (+41 22) 702 50 50
Fax: (+41 22) 702 58 58
Electronic mail address: swiss-prot at expasy.org
WWW server: http://www.expasy.org/

Protein Information Resource (PIR)
Georgetown University Medical Center
3300 Whitehaven Street NW
Suite 1200
Washington, DC 20007
United States of America
Telephone: (+1 202) 687 1039
Fax: (+1 202) 687 0057)
Electronic mail address: pirmail at georgetown.edu
WWW server: http://pir.georgetown.edu

Sincerely,

UniProt Help Desk

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