From dw2237 from wayne.edu Mon Nov 2 07:19:06 2009 From: dw2237 from wayne.edu (Michele Donato) Date: Mon Nov 2 11:06:18 2009 Subject: [Computational-biology] Call for Papers: IEEE CIBCB '10 Message-ID: <2018980590.56981257164346798.JavaMail.root@starship.merit.edu> Call for Papers: IEEE CIBCB 2010 2010 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology 2-5 May 2010, Montreal, Canada IMPORTANT DATES: Special Session Proposals Due: 15 Nov. 2009 Tutorial Proposals Due: 15 Nov. 2009 Paper submission deadline: 15 Dec. 2009 Author notification: 15 Feb. 2010 Camera-ready paper deadline: 15 Mar. 2010 Conference: 2-5 May 2010 ----------------------------------------------------------------- SCOPE: This symposium will bring together top researchers, practitioners, and students from around the world to discuss the latest advances in the field of Computational Intelligence and its application to real world problems in biology, bioinformatics, computational biology, chemical informatics, bioengineering and related fields. Computational Intelligence (CI) approaches includes artificial neural networks, fuzzy logic, evolutionary algorithms, hybrid approaches and other emerging techniques. Topics of interest include, but are not limited to: - high-throughput data analysis (microarrays, mass spectrometry, EST, etc.) - molecular docking and drug design - RNA and protein folding and structure prediction - metabolic pathway analysis - analysis of large biological data sets - single nucleotide polymorphism (SNP) analysis - immuno- and chemo-informatics - molecular evolution and phylogenetics - bio and medical ontologies - microRNA gene expression analysis - molecular sequence alignment and analysis - systems and synthetic biology - emergent properties in complex biological system - computational proteomics - motif and signal detection - medical image analysis and pattern recognition - in-silico optimization of biological systems The use of computational intelligence must play a substantial role in submitted papers. Submissions will be peer reviewed and accepted papers will be published in the conference proceedings and will be indexed in IEEE eXplore. SUBMISSION PROCEDURE: Prospective authors are invited to submit papers of no more than eight (8) pages in IEEE conference format, including results, figures and references. Submission details can be found on the symposium web site at: www.cibcb.org/CIBCB2010. Authors are expected to present their paper at the symposium. CALL FOR SPECIAL SESSIONS and TUTORIALS: Consult the CIBCB'10 symposium web site for instructions on proposing a special session or tutorial. Papers for special sessions must have significant computational intelligence content. LOCATION: The symposium will take place at the Hotel Omni Mont-Royal located in beautiful downtown Montreal close to the University of Montreal and McGill University ORGANIZING COMMITTEE: General Chair L. Gwenn Volkert Program Chair: Dan Ashlock Technical Co-Chairs: Francesco Masulli Mihail Popescu Clare Bates Congdon Publicity Chair: Sorin Draghici Proceedings Chair: Chengpeng (Charlie) Bi Finance Chair: Gary Fogel ---------------------------------------------------------------------- Direct your questions or requests for additional information to: L. Gwenn Volkert ? volkert@cs.kent.edu - CIBCB 2010 General Chair or Daniel Ashlock - dashlock@uoguelph.ca - CIBCB 2010 Program Chair or visit: http://www.cibcb.org/CIBCB10 http://www.cibcb.org/files/cibcb2010cfp.pdf From Robin.Haw from oicr.on.ca Mon Nov 2 11:29:52 2009 From: Robin.Haw from oicr.on.ca (Robin Haw) Date: Mon Nov 2 14:55:18 2009 Subject: [Computational-biology] Reactome Pathway Database User Survey Message-ID: Reactome is a curated database of core pathways and reactions in human biology. Information is authored by expert biological researchers, maintained by the Reactome editorial staff and cross-referenced to several third-party databases. Reactome has an entity-level pathway viewer and data mining tools to facilitate searching and visualizing pathway data and the analysis of user-supplied data sets. Furthermore, Reactome has increased its utility to the model organism communities with improved orthology prediction methods allowing pathway inference for 22 species. Reactome's data content and software can all be freely used and redistributed under open source terms. Reactome is committed to providing access to high-quality pathway information and helpful data analysis tools. With this in mind, we are actively soliciting comments from the research community in order to assess community needs. We are interested to hear about your experience with Reactome, and would like to know a bit about your background and research interests so that we can continue to improve the Reactome site and tools. You can access the survey at: http://tinyurl.com/l48zzq Thank you for taking part. Robin Haw Manager of Reactome Outreach http://www.reactome.org From r.zangi from ikerbasque.org Wed Nov 4 09:20:35 2009 From: r.zangi from ikerbasque.org (Ronen Zangi) Date: Wed Nov 4 11:59:52 2009 Subject: [Computational-biology] Ph.D. Position in Computational Biophysical Chemistry Message-ID: <4AF18DB3.8030208@ikerbasque.org> Ph.D. Position in Computational Biophysical Chemistry A four year Ph.D. fellowship is available in the faculty of Chemistry at the University of the Basque Country, San Sebastian Spain. The Ph.D. project will make use of computational methods to investigate several issues in epigenetics that involve DNA-protein recognition. In particular, the driving force that governs the selectivity of hemi-methylated DNA by the regulatory protein UHRF1, as well as, the base flipping mechanism associated with this interaction. These studies will utilize molecular dynamics simulations and several techniques in free energy calculations. The candidate should have a Master (or an equivalent) degree in chemistry, physics, biology, or a related area, preferably from an EU country. The starting date of the position is flexible. For more information contact Prof. Ronen Zangi: r.zangi@ikerbasque.org From jprudhomme from healthtech.com Wed Nov 4 15:23:09 2009 From: jprudhomme from healthtech.com (Jim Prudhomme) Date: Wed Nov 4 16:56:47 2009 Subject: [Computational-biology] Microsoft and Oracle Showcase Informatics Solutions at... Message-ID: <013c01ca5d8c$9feca090$dfc5e1b0$@com> CHI's 2nd Annual Adopting R&D Informatics Systems: Data Management, Integration & Knowledge Management February 3-5, 2010 Moscone North Convention Center - San Francisco, CA Register by November 20 at the Early Bird Discount! www.tri-conference.com/ird.asp Key Benefits of Attending this Conference: Network with senior level informatics experts and IT professionals at conference sessions dedicated to: - Executive Strategies-Integrated R&D Informatics - Data Information and Knowledge Management - Integrative Data Management through Cloud, Wikis, Ontologies & Semantic Web - Translational Informatics-How Far Have We Come? - Integrated Genomic, Biology, And Image Data Participate in Break-out discussion groups on focused these topics: E-Notebooks - The Power House of Integration? Moderator: David M. Sedlock, Ph.D., Senior Director, Research & Development Systems, Millennium, The Takeda Oncology Company - Data Integration vs. System Integration - Value and Pitfalls of ELN Integration - Vendor Role (Impact of Customization) - Alternatives to ELN System Integration - ELN vs. LIMS vs. SDMS - How Do These Systems Achieve Maximum Value? Ontologies and Semantic Web Moderator: Susie Stephens, Director, Biomedical Informatics, Pharmaceutical Research & Development, Johnson & Johnson - Is there a cloud in your future? - Aggregation of key information from sources including structural chemical and biological data along with predictions of activity Open Source Data Standards Moderator: Ajay Shah, Ph.D., MBA, PMP, Director, Research Informatics, Elan Pharmaceuticals, Inc. - Open source and public platforms - Role of Open Source Technology in Systems Design - Virtual Pharmaceutical collaborations Attend our Poster session to learn about new, innovative research and informatics techniques. View Informatics platforms and tools presented by Technology Service Providers in the Exhibit Hall. Sponsorship and Exhibit Opportunities are Available! For details on customized packages, contact Carol Dinerstein at +1 781-972-5471, dinerstein@healthtech.com or Jon Stroup at +1 781-972-5483, jstroup@healthtech.com Group Discounts are Available! CHI will work within your company's budget to send your team to this conference. For details, contact David Cunningham at +1 781-972-5472, cunningham@healthtech.com View the full agenda and register at www.tri-conference.com/ird.asp Contact for more information: James Prudhomme Marketing Manager Cambridge Healthtech Institute 250 First Avenue, Suite 300 Needham, MA 02494 Tel: 781-972-5400 Fax: 781-972-5425 jprudhomme@healthtech.com From y.ghanbari from gmail.com Wed Nov 4 15:37:21 2009 From: y.ghanbari from gmail.com (Yasser) Date: Wed Nov 4 16:56:54 2009 Subject: [Computational-biology] Re: Some Wavelet applications on Speech Enhancement References: Message-ID: I like this paper published in Journal of Speech Communication: http://lyle.smu.edu/~yghanbari/Speech_Communication_2006.pdf From y.ghanbari from gmail.com Wed Nov 4 15:42:06 2009 From: y.ghanbari from gmail.com (Yasser) Date: Wed Nov 4 16:56:58 2009 Subject: [Computational-biology] A Graph-Laplacian-Based Feature Extraction Algorithm for Neural Spike Sorting Message-ID: <23d9190b-0760-45ed-b617-741b8568e6f9@j19g2000vbp.googlegroups.com> PDF: http://lyle.smu.edu/~yghanbari/EMBC09_FinalSubmission_YasserGhanbari_0876.pdf ABSTRACT: Analysis of extracellular neural spike recordings is highly dependent upon the accuracy of neural waveform classification, commonly referred to as spike sorting. Feature extraction is an important stage of this process because it can limit the quality of clustering which is performed in the feature space. This paper proposes a new feature extraction method (which we call Graph Laplacian Features, GLF) based on minimizing the graph Laplacian and maximizing the weighted variance. The algorithm is compared with Principal Components Analysis (PCA, the most commonly-used feature extraction method) using simulated neural data. The results show that the proposed algorithm produces more compact and well-separated clusters compared to PCA. As an added benefit, tentative cluster centers are output which can be used to initialize a subsequent clustering stage. From mcdevitt from ibb.gatech.edu Wed Nov 4 16:21:19 2009 From: mcdevitt from ibb.gatech.edu (Megan McDevitt) Date: Thu Nov 5 12:24:29 2009 Subject: [Computational-biology] International Conference - Genome Biology and Bioinformatics Message-ID: The program of the conference features talks of many leading experts in the field Visit the speakers page of the website [http://www2.isye.gatech.edu/binf2009/speakers_2009.php] Thanks to financial support from a larger group of sponsors we are happy to announce that the registration fee is reduced to $20 student/postdoc; $50 - academic; $100 - industry; We hope to see you soon in the Georgia Tech Ferst Center for the Arts . Visit the website. [http://www2.isye.gatech.edu/binf2009/] November 12 (starting at 5pm) Dr. Jeffrey Bennetzen, Member of National Academy of Sciences, University of Georgia, Athens, GA, USA The Hyperevolution of Artifacts and Realities in the Structure and Function of Higher Plant Genomes Dr. Jian Ma, University of Illinois at Urbana Champaign, Urbana, IL, USA Unraveling the Ancestral Mammalian Genome Yields Insights into the Human Genome Dr. Igor Jouline (Zhulin), University of Tennessee - Oak Ridge National Laboratory, Oak Ridge, TN, USA Molecular Evolution of a Complex Signal Transduction System in Prokaryotes Dr. Curtis Huttenhower, Harvard University, Boston , MA, USA Large Scale Genomic Data Mining Dr. Boris Lenhard, University of Bergen, Norway Long-, Short- and Mid-Range Gene Regulation: Lessons from Genome -Wide Patterns of Sequence Conservation and Transcription Factor Binding Inaugural Margaret O. Dayhoff lecture Dr. David Lipman, Member of the National Academy of Sciences, NCBI/NIH, Bethesda, MD, USA Margaret Dayhoff and Molecular Evolution in the 21st Century Dr. Joanna Masel, University of Arizona, Tucson, AZ, USA The Origin of New Coding Sequences Dr. Nick Grishin, Howard Hughes Medical Institute, University of Texas, Dallas, TX, USA Evolutionary Classification of Protein Structures Dr. Eugene Koonin, NCBI/NIH, Bethesda, MD, USA Systems Biology and the Prospects of a Post-Modern Evolutionary Synthesis Dr. Nikos Kyrpides, DOE Joint Genome Institute, Walnut Creek, CA, USA The Future of Microbial Genomics Dr. Andrei Osterman, Burnham Institute for Medical Research, La Jolla, CA USA Integrated Genomic Reconstruction of Metabolic and Regulatory Networks in Bacteria November 14 Dr. Pierre Rouze, Gent University, Gent, Belgium >From Protists to Plants, Fungi and Animals: Eukaryote Genomes Are Not Born Equal Dr. Jason Miller, J. Craig Venter Institute, Rockville, MD, USA Studies of the Human Microbiome Dr. Mark Borodovsky, Georgia Tech and Emory University, Atlanta, GA, USA Gene Finding in the Era of Next Generation Sequencing Dr. John Reinitz, State University of New York at Stony Brook, NY, USA When Two Plus Two Doesn't Equal Four: Modeling Non-Modular Enhancer Behavior in the Eve Promoter Dr. Yael Mandel -Gutfreund, Technion, Institute of Technology, Haifa, Israel Deciphering the Role of Alternative Splicing in Modulating the Human Gene Regulatory Network Dr. Andrey Mironov, Moscow State University, Russia Conserved Intronic RNA Secondary Structures Dr. Gill Bejerano, Stanford University, Stanford, CA, USA Genomics and the Evolution of Human-Specific Traits Dr. King Jordan, Georgia Tech, Atlanta, GA, USA MIR Elements Provide Chromatin Boundaries to the Human Genome Dr. Vineet Bafna, University of California at San Diego, USA Proteogenomics Conference ends at 9pm, November 14 Visit the Website [http://www2.isye.gatech.edu/binf2009] Questions? Contact Megan McDevitt, Event Manager This email was sent to comp-bio@net.bio.net. You can instantly unsubscribe from these emails by clicking here http://institutebioengineeringbiosciences.createsend.com/t/r/u/hdklhu/jltkkltur/. From jeedward from yahoo.com Sun Nov 8 19:05:02 2009 From: jeedward from yahoo.com (John Edward) Date: Sun Nov 8 23:09:29 2009 Subject: [Computational-biology] BCBGC-10 Call for papers Message-ID: <120.58079.qm@web45911.mail.sp1.yahoo.com> BCBGC-10 Call for papers ? The 2010 International Conference on Bioinformatics, Computational Biology, Genomics and Chemoinformatics (BCBGC-10) (website: http://www.PromoteResearch.org) will be held during 12-14 of July 2010 in Orlando, FL, USA. ?BCBGC is an important event in the areas of bioinformatics, computational biology, genomics and chemoinformatics and focuses on all areas related to the conference. ? The conference will be held at the same time and location where several other major international conferences will be taking place. The conference will be held as part of 2010 multi-conference (MULTICONF-10). MULTICONF-10 will be held during July 12-14, 2010 in Orlando, Florida, USA. The primary goal of MULTICONF is to promote research and developmental activities in computer science, information technology, control engineering, and related fields. Another goal is to promote the dissemination of research to a multidisciplinary audience and to facilitate communication among researchers, developers, practitioners in different fields. The following conferences are planned to be organized as part of MULTICONF-10. ? International Conference on Artificial Intelligence and Pattern Recognition (AIPR-10) ?International Conference on Automation, Robotics and Control Systems (ARCS-10) International Conference on Bioinformatics, Computational Biology, Genomics and Chemoinformatics (BCBGC-10) International Conference on Computer Networks (CN-10) International Conference on Enterprise Information Systems and Web Technologies (EISWT-10) International Conference on High Performance Computing Systems (HPCS-10) International Conference on Information Security and Privacy (ISP-10) International Conference on Image and Video Processing and Computer Vision (IVPCV-10) International Conference on Software Engineering Theory and Practice (SETP-10) International Conference on Theoretical and Mathematical Foundations of Computer Science (TMFCS-10) ? We invite draft paper submissions. Please see the website http://www.PromoteResearch.org for more details. ? Sincerely John Edward Publicity committee From enquire from iqpc.co.uk Tue Nov 10 06:49:42 2009 From: enquire from iqpc.co.uk (Courtney Becker-James) Date: Tue Nov 10 08:03:53 2009 Subject: [Computational-biology] International Speaker Line-up Announced for Pharma IQ's Next-Generation DNA Sequencing Message-ID: <6f4d6b1f-835c-421c-aaa8-a6ba030ab5ed@xtinmta08.xt.local> http://www.dnaevent.com/ Dear Colleague, Today's Next-Generation DNA Sequencing systems are opening novel fields and applications in biology studies and medical research. Beyond genomic sequencing, of which there are now many successful results, the technology is also allowing scientists to pursue: - Personal genomics with detailed analysis of individual genome stretches - Precise analysis of RNA transcripts for gene expression - Genome-wide characterisation and profiling of mRNAs, small RNAs and transcription factor regions - Structure of chromatin and DNA methylation patterns - Microbiology and metagenomics At Pharma IQ's Next-Generation DNA Sequencing conference, January 18th - 20th in London, you will share study and technology pilot results with peers on how to utilise NGS systems to predict disease risk at genome level by using next- generation systems to accurately scan and identify rare variants in genes, short sequence repeats and CNPs. You will also discuss with other principal investigators how they're evaluating the right next generation approach for their research project, comparing deep vs. wide, de novo vs. re-sequencing and conventional microarray platforms. The international speaker panel includes: - Dr Nicholas H. Bergman, Principal Investigator and Genomics Team Leader, National Biodefense Analysis and Countermeasures Center - Dr Nick Loman, Head of Bioinformatics, University of Birmingham - Dr Daniel J. Turner, Head of Sequencing Technology Development, Wellcome Trust Sanger Institute - Dr Ina Vandenbroucke, Senior Scientist, Translational Genetics & Genomics, Tibotec - Virco BVBA - Dr Joris Veltman Department of Human Genetics, Radboud University Nijmegen Medical Centre - Dr Bhupinder Bhullar , Laboratory Head, Biomedical Research, Novartis - Dr Harma Feitsma, Research Scientist Molecular Diagnostics, Philips Research Labs - Dr Peter Verhasselt, Principal Scientist, Translational Genomics & Genetics, Johnson & Johnson Pharmaceutical Research & Development - Guy Cochrane, Team Leader, European Nucleotide Archive Team, European Bioinformatics Institute - Roderic Guigo, Senior Group Leader, Genomic Regulations, Biomedical Informatics, IMIM-Hospital del Mar - Bernd Timmermmann, Next Generation Sequencing Service Group, Max Planck Institute for Molecular Genetics Don't miss this opportunity to hear from leading practitioners and technology users. Download the brochure for further information about the agenda: http://www.dnaevent.com/Event.aspx?id=234806 NGS systems are rapidly evolving. However many challenges remain, including the development of robust protocols for generating sequencing libraries, building effective new approaches to data-analysis and often a rethinking of experimental design. Sign up today for January's Next-Generation DNA Sequencing meeting to discuss how to overcome these challenges with other practitioners. If you sign up before 20th November 2009, you can SAVE up to 400 GBP off the standard rates. Plus the first 10 academics to book on can take advantage of registering for only 399 GBP (+VAT)! For further information on the savings you could make, visit the website: http://www.dnaevent.com/Event.aspx?id=234808 We look forward to meeting you in London in January. Sincerely, Courtney Becker-James Conference Director Pharma IQ PS: If you know who this meeting is most relevant for, please forward it to them so they have the opportunity to join their peers at this unique gathering! This email was sent by:IQPC Ltd. Anchor House 15-19 Britten Street, London, SW3 3QL, United Kingdom http://cl.exct.net/profile_center.aspx?s=fe551c797160077e761c&mid=ff2912787067&j=fe5c167274670c7a7312&l=fe641576776301787414&jb=ffcf14&ju= Update Profile http://cl.exct.net/unsub_center.aspx?s=fe551c797160077e761c&j=fe5c167274670c7a7312&mid=ff2912787067&lid=fe641576776301787414&jb=ffcf14&ju= Unsubscribe From jqb from Cs.Nott.AC.UK Wed Nov 11 05:46:52 2009 From: jqb from Cs.Nott.AC.UK (Jaume Bacardit) Date: Wed Nov 11 12:33:26 2009 Subject: [Computational-biology] Reminder - Call for GECCO 2010 workshop proposals - Deadline November 16th Message-ID: <4AFA961C.2030005@cs.nott.ac.uk> Our apologies if you receive multiple copies of this announcement. CALL FOR WORKSHOP PROPOSALS 2010 GENETIC AND EVOLUTIONARY COMPUTATION CONFERENCE (GECCO-2010) Sponsored by ACM SIGEVO http://www.sigevo.org/GECCO-2010 The GECCO-2010 Program Committee invites proposals for workshops to be held in conjunction with the 2010 Genetic and Evolutionary Computation Conference (GECCO-2010) in Portland, Oregon, USA, July 7-11. ** Important Dates ** Deadline for Workshop Proposals: November 16th, 2009 Notification of Acceptance: November 30th, 2009 Information and Submissions: jqb@cs.nott.ac.uk GECCO workshops provide an excellent opportunity to meet people with similar interests, to be exposed to cutting-edge research and to exchange ideas in an informal setting. Ideally, a GECCO workshop should focus on a specialized research area, on an emerging research field, or on interdisciplinary research area between the genetic and evolutionary computation community and other research fields. GECCO workshops can be two hours, half day, or a full day long. The format can be decided by the organizers who are encouraged to plan interactive sessions (e.g, debate/discussion sessions, brainstorming or problem solving sessions) which cannot be easily accommodated in the GECCO conference program. Proposals should be mailed to: jqb@cs.nott.ac.uk Each proposal must be submitted as a plain text file and must contain the following information: 1. A half page description of the workshop including a clear description of the specific topics issues on which the workshop will focus should be identified. 2. A brief (half page) discussion of why the topic is of interest to the genetic and evolutionary computation community and about the workshop target audience. 3. The estimated number of potential attendees, accepted papers and submissions. If a previous edition of the workshop has already taken place, then the previous number of submissions, accepted papers, and attendees should be included. 4. A draft schedule of the workshop (with a duration of either 2 hours, half day or a full day) highlighting the planned discussion sessions (panels, Q&A, hands-on demonstrations, problem-solving sessions, brainstorming, etc.) 5) The complete contact information of the workshop organizers (Postal address, E-mail, phone and fax numbers, & WWW page). 6) A brief biography of the organizers. The proposal should be accompanied by the full CVs of the organizers in PDF format. These should include previous experience in workshop or conference organization. The organizers of an accepted workshop are responsible for its coordination, for its publicity (e.g., for sending out call for papers), for collecting and reviewing the papers, for providing a list of accepted papers and their authors, if applicable. Attendance at the workshops will be open to all GECCO attendees. Note that *all* organizers, participants and presenters must register to the GECCO-2010 conference. Organizers of a workshop *do not* qualify for a reduction in the registration or accommodation costs at the conference. Accepted workshop papers will be collected by Sheridan/ACM Press, and published in a separate workshop proceedings volume. Details and additional deadlines will be provided once it has been decided which workshops will be accepted for GECCO-2010. All accepted Workshop Papers must use the ACM template for papers and must follow all ACM formatting rules. Accepted workshop papers that do not use the ACM template and/or do not adhere to ACM formatting rules will not be published. The deadline for the submission of workshop proposal is November 16, 2009. Proposals should be submitted as plain text files (no HTML) with the exception of the CVs which have to be submitted as PDFs. Workshop organizers will be notified by November 30th whether the workshop proposal has been accepted. GECCO is sponsored by the Association for Computing Machinery Special Interest Group on Genetic and Evolutionary Computation (SIGEVO). SIG Services: 2 Penn Plaza, Suite 701, New York, NY, 10121, USA, 1-800-342-6626 (USA and Canada) or +212-626-0500 (Global). This message has been checked for viruses but the contents of an attachment may still contain software viruses, which could damage your computer system: you are advised to perform your own checks. Email communications with the University of Nottingham may be monitored as permitted by UK legislation. From HISHAM from uhcl.edu Wed Nov 11 18:56:52 2009 From: HISHAM from uhcl.edu (Al-Mubaid, Hisham) Date: Thu Nov 12 12:58:38 2009 Subject: [Computational-biology] BICoB-2010 CFP - paper Deadline Extended: November 23, 2009 Message-ID: <4B57CB6706E6144C9D5D960FEEDA8E8E029A92DB@EXUHCL1.pclab.uhcl.edu> Submission Deadline Extended: November 23, 2009 *** We apologize if you receive multiple copies of this CFP *** **************************************************** BICoB-2010 - Call for Papers http://sce.uhcl.edu/bicob10/ 2nd International Conference on Bioinformatics and Computational Biology (BICoB) March 24 - 26, 2010, Honolulu, Hawaii, USA Full paper Submission Deadline:...............................November 23, 2009 Notification of Acceptance: ..................................... December 23, 2009 Pre-registration and Camera-ready paper due:...... January 15, 2010 Computational techniques have already enabled unprecedented advances in modern biology and medicine. This continues to be a vibrant research area with broadening of computational techniques and new emerging challenges. The Bioinformatics and Computational Biology (BICoB) conference was established by the ISCA to promote the advancement of computing techniques and their application to life sciences. T he BICoB conference will feature original unpublished research in all areas of bio-informatics and computational biology, and covering the entire spectrum of underlying computational techniques/models/paradigms. The topics of interest include (and are not limited to): * Genome analysis: Genome assembly, genome and chromosome annotation, gene finding, alternative splicing, EST analysis and comparative genomics. * Sequence analysis: Multiple sequence alignment, sequence search and clustering, function prediction, motif discovery, functional site recognition in protein, RNA and DNA sequences. * Phylogenetics: Phylogeny estimation, models of evolution, comparative biological methods, population genetics. * Structural Bioinformatics: Structure matching, prediction, analysis and comparison; methods and tools for docking; protein design * Analysis of high-throughput biological data: Microarrays (nucleic acid, protein, array CGH, genome tiling, and other arrays), EST, SAGE, MPSS, proteomics, mass spectrometry. * Genetics and population analysis: Linkage analysis, association analysis, population simulation, haplotyping, marker discovery, genotype calling. * Systems biology: Systems approaches to molecular biology, multiscale modeling, pathways,gene networks. SUBMISSION PROCEDURES BICoB welcomes submissions in all areas of computing with impact on life sciences including (but not limited to) algorithms, databases, languages, systems, and high performance computing. For example: - Parallel and high-performance techniques - Unifying computational techniques - Data and image mining techniques - Approximation and randomized algorithms and systems - Computational biology on emerging architectures and hardware accelerators Papers will be accepted only by electronic submission (PDF only). A full paper, including title, author's name(s) and affiliation, mailing address, telephone, fax and email of the principal author, should be submitted by November 23, 2009 at the following web site: https://cmt.research.microsoft.com/BICOB2010/ The submitted manuscript should closely reflect the final paper as it will appear in the Proceedings which will be a maximum of 6 pages (+2 pages with additional page charge). ISCA double-column format will be used. See http://www.isca-hq.org/sample-isca-manuscript-format.pdf . Latex users: http://www.isca-hq.org/Latex-format.htm If you encounter any difficulties during submission or if you require further information, please contact: isca@ipass.net. Authors wishing to have their papers reviewed for possible publication in the ISCA Journal of Computers and Applications should send by postal mail or email expanded versions of their papers directly to the Editor, Prof. David Jeff Jackson. (See Instructions to Authors at: http://www.isca-hq.org/j-authr.htm ) ................................................... IMPORTANT DATES Full paper Submission Deadline: ......................................November 23, 2009 Notification of Acceptance: ............................................... December 23, 2009 Pre-registration and Camera-ready paper due:................ January 15, 2010 CONFERENCE CHAIR George Karypis University of Minnesota karypis@cs.umn.edu PROGRAM CHAIRS Hisham Al-Mubaid University of Houston-Clear Lake hisham@uhcl.edu If you would like to be removed from our distribution list, please reply to this email with the word 'REMOVE' in the Subject line. Mary Ann Sullivan Executive Director, ISCA International Society for Computers and Their Applications 975 Walnut Street, Suite 132 Cary, NC 27511 USA Phone: 919-467-5559 FAX: 919-467-3430 E-mail: isca@ipass.net From quaglia from disi.unitn.it Thu Nov 12 13:28:48 2009 From: quaglia from disi.unitn.it (Paola Quaglia) Date: Thu Nov 12 15:26:33 2009 Subject: [Computational-biology] Deadline extension - FBTC 2010, From Concurrency To Biology and back Message-ID: <200911121828.nACISkox025094@disi.unitn.it> [Apologies for multiple posting] ** Deadline Extension ** 3rd Workshop "From Biology To Concurrency and back" (FBTC 2010) ** New deadline for abstracts: November 29, 2009 (abstracts) ** New deadline for papers: December 8, 2009 More information below or at http://www.disi.unitn.it/~fbtc2010/ ================================================================================ CALL FOR PAPERS: FBTC 2010 From Biology To Concurrency and back (satellite event of ETAPS 2010) March 27, 2010 Paphos, Cyprus http://www.disi.unitn.it/~fbtc2010/ ================================================================================ AIMS AND OBJECTIVES As in its previous editions, the workshop aims at gathering researchers with special interest at the convergence of life and computer science, with particular focus on the application of techniques and tools from concurrency. We solicit the submission of unpublished results reporting on both modelling, analysis, and validation of biological behaviours using concurrency-inspired methods and platforms, and on bio-inspired models and tools for describing distributed interactions. Topics of interest include, but are not limited to: applications of techniques from rewriting logics, process calculi, Petri Nets, graph grammars, hybrid systems, and model checking to the representation and testing of scenarios from life sciences. SUBMISSION AND PUBLICATION Submission through EasyChair, 15 pages manuscripts in EPTCS (http://www.eptcs.org/) style. IMPORTANT DATES Submission of title and abstract: November 29, 2009 Submission of paper: December 8, 2009 Notification: January 17, 2010 Submission of final version: February 21, 2010 PROGRAMME COMMITEE (to be confirmed) Marco Antoniotti (University of Milan Bicocca, IT) Chiara Bodei (University of Pisa, IT) Luca Bortolussi (University of Udine, IT) Luca Cardelli (Microsoft Research Cambridge, UK) Erik de Vink (Technische Universiteit Eindhoven, NL) Vincent Danos (CNRS and University of Edinburgh, UK) Fran?ois Fages (INRIA Paris-Rocquencourt, F) Anthony Finkelstein (University College London, UK) Walter Fontana (Harvard Medical School, US) Radu Grosu (Stony Brook University, US) Jane Hillston (University of Edinburgh, UK) Anna Ing?lfsd?ttir (Reykjavik University, IS) John Lygeros (Automatic Control Laboratory, CH) Emanuela Merelli (University of Camerino, IT) (Co-chair) Paola Quaglia (CoSBi and Trento University, IT) (Co-chair) Carolyn Talcott (SRI International, US) Adelinde Uhrmacher (University of Rostock, DE) Cristian Versari (University of Bologna, IT) From hiraghuraman from gmail.com Tue Nov 17 05:32:13 2009 From: hiraghuraman from gmail.com (Raghu) Date: Tue Nov 17 11:43:31 2009 Subject: [Computational-biology] Eco allele Message-ID: <4b02f36f-927a-457c-8a20-cffec410a806@m33g2000pri.googlegroups.com> Hello friends, What are eco-alleles? Please answer From karypis from cs.umn.edu Fri Nov 13 15:01:06 2009 From: karypis from cs.umn.edu (George Karypis) Date: Tue Nov 17 12:23:13 2009 Subject: [Computational-biology] 2nd CFP: HiCOMB 2010 - 9th IEEE International Workshop on High Performance Computational Biology Message-ID: <00c801ca649c$09d329f0$1d797dd0$@umn.edu> -=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=- Call For Papers HiCOMB 2010 9th IEEE International Workshop on High Performance Computational Biology http://www.hicomb.org/ held in conjunction with the International Parallel and Distributed Processing Symposium http://www.ipdps.org/ Monday, April 19, 2010 Atlanta, Georgia -=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=- Computational Biology are related disciplines are fast emerging as an important area for academic research and industrial application. The large size of biological data sets, inherent complexity of biological problems and the ability to deal with error-prone data all result in large run-time and memory requirements. The goal of this workshop is to provide a forum for discussion of latest research in developing high-performance computing solutions to problems arising from molecular biology and related life sciences areas. We are especially interested in parallel algorithms, memory-efficient algorithms, large scale data mining techniques, and design of high-performance software. The workshop will feature contributed papers as well as invited talks from reputed researchers in the field. Topics of interest include but are not limited to: * Bioinformatic databases * Computational genomics * Computational proteomics * DNA assembly, clustering and mapping * Gene expression and microarrays * Gene identification and annotation * Parallel algorithms for biological analysis * Parallel architectures for biological applications * Molecular evolution * Molecular sequence analysis * Phylogeny reconstruction algorithms * Protein structure prediction and modeling * String data structures and algorithms * Parallel algorithms in chemical genetics and chemical informatics Submission Guidelines: ---------------------- Papers reporting original research (both theoretical and experimental) in all areas of bioinformatics and computational biology are sought. Surveys of important recent results and directions are also welcome. To submit a paper, upload a postscript or PDF copy of the paper from the workshop web page (http://www.hicomb.org/). The paper should not exceed 12 single-spaced pages (US Letter or A4 size) in 11pt font or larger. All papers will be reviewed. IEEE CS Press will publish the IPDPS symposium and workshop abstracts as a printed volume. The complete symposium and workshop proceedings will also be published by IEEE CS Press on CD-ROM and will also be available in the IEEE Digital Library. Important Dates: ---------------- November 30, 2009 Workshop Submissions Due December 25, 2009 Author Notification February 1, 2009 Camera-ready Paper Due Workshop Co-Chairs: ------------------- David A. Bader College of Computing Georgia Institute of Technology Atlanta, GA 30332 USA Phone: +1.404.894.3152 http://www.cc.gatech.edu/~bader Srinivas Aluru Dept. of Electrical & Computer Engg. Iowa State University 3227 Coover Hall Ames, IA 50011 USA Phone: +1.515.294.3539 Email: aluru@iastate.edu Program Chair: -------------- George Karypis Dept. of Computer Science & Engineering University of Minnesota Minneapolis, MN 55455 Email: karypis@cs.umn.edu http://www.cs.umn.edu/~karypis Program Committee: ------------------ Pratul K. Agarwal, Oak Ridge National Laboratory, USA Inanc Birol, Genome Sciences Centre, British Columbia, Canada Georg Fuellen, University of Rostock, Rostock, Germany Ananth Grama, Purdue University, Indiana, USA Mark Miller, San Diego Supercomputer Center, California, USA Sandeep Patel, University of Delaware, USA Andrew Rau-Chaplin, Dalhousie University, Nova Scotia, Canada Huzefa Rangwala, George Mason University, Virginia, USA Jared Simpson, Wellcome Trust Sanger Institute, Cambridge, UK Alexandros Stamatakis, Technische Universit?t Munchen, Munich, Germany John Stone, University of Illinois at Urbana-Champaign, USA Evripidis Sotiriadis, Tech. Univ. of Crete, Greece Denis Trystram, LIG, France Chau-Wen Tseng, University of Maryland, College Park, USA Ian Watson, Lilly, Indiana, USA Tiffani Williams, Texas A&M University, Texas, USA Ying Zhao, Tsinghua University, Beijing, China Albert Zomaya, University of Sydney, Sydney, Australia From jprudhomme from healthtech.com Tue Nov 17 14:52:00 2009 From: jprudhomme from healthtech.com (Jim Prudhomme) Date: Tue Nov 17 15:02:32 2009 Subject: [Computational-biology] Adopting R&D Informatics Systems Message-ID: <001101ca67bf$6d6090e0$4821b2a0$@com> Part of the Informatics Channel at CHI's 17th International Molecular Medicine Tri-Conference. Cambridge Healthtech Institute's Second Annual Adopting R&D Informatics Systems: Data Management, Integration & Knowledge Management February 3-5, 2010 Moscone North Convention Center * San Francisco, CA Register by November 20 and Save up to $350: http://www.tri-conference.com/ird.asp Speaker Presentations: Enterprise Scientific Workflow Environment Drives Innovation Juergen Hammer, Ph.D., M.B.A., Pharma Research Scientific Informatics; Global Head, In Silico Sciences; Center Head, Scientific Informatics, F. Hoffmann-La Roche, Inc. The Pistoia Alliance, Inc.-A Construct for Precompetitive Collaboration Chris Waller, Ph.D., Senior Director, Precompetitive Collaborations, Research, Development & Medical Informatics, Worldwide Technology, Pfizer, Inc. Recent Strategies with Cloud, Wikis, Ontologies and Open Source Data Standards Giles M. Day, Senior Director, BBC Informatics, Pfizer, Inc. Luncheon Presentation Sponsored by Microsoft Personalized Medicine: The Missing Pieces Jim Karkanias, Senior Director of Applied Research & Technology, Microsoft Health Solutions Group Integrated Informatics Systems for R&D John Reynders, Ph.D., CIO, Pharmaceutical Research & Development, Johnson & Johnson Executive Panel with Q&A Are We Integrating the Right Data: Extending Beyond Laboratory Data to Decisions Impacting Project Success Moderator: David M. Sedlock, Ph.D., Senior Director, Research & Development Systems, Millennium, The Takeda Oncology Company Presentation Sponsored by Accelrys Knowledge Management David Hodgson, Ph.D., Site Head, Global Research Informatics, Roche Palo Alto Knowledge for Strategic Advantage: Accelerating the R&D Cycle Thomas P. Hill, Principal, The Leverage Innovation Group; former Director, Learning and Knowledge Management, Genentech ASAP-Emphasizing Multidimensional Drug Discovery W. Patrick Walters, Ph.D., Senior Research Fellow & Group Head, Computational Drug Discovery Technologies, Vertex Pharmaceuticals, Inc. Agile Software Development: Meeting the Rapidly Changing Needs in Drug Discovery Man-Ling Lee, Ph.D., Senior Program Analyst, Discovery Chemistry, Small Molecule Drug Discovery, Genentech, Inc. Application of Translational Informatics in Tailored Therapeutics Susie Stephens, Director, Biomedical Informatics, Pharmaceutical Research & Development, Johnson & Johnson Data Integration-What's in it for Me? Randal Chen, Ph.D., Director, Research Informatics, Amgen, South San Francisco Integrative Data Mining for Drug Discovery using the Semantic Web Michael Lajiness, Ph.D., Research Scientist, Structural and Computational Sciences, Eli Lilly & Company Collaborative Drug Discovery Humanitarian and Commercial Researcher Network Case Studies Barry A. Bunin, Ph.D., Chief Executive Officer & President, Collaborative Drug Discovery (CDD), Inc. Panel: Drug Discovery Collaborations in 2010 Moderator: Barry A. Bunin, Ph.D., Chief Executive Officer & President, Collaborative Drug Discovery (CDD), Inc. Implementing a Translational Biomarker Strategy to Reduce Attrition in Drug Development Irina Antonijevic, M.D., Ph.D., Director, Translational Research, Biological Research, Lundbeck Research, Inc. USA High Content Mining of Disease Biomarkers Jake Chen, Ph.D., Assistant Professor, Informatics & Computer Science, Indiana University School of Informatics; Director, Indiana Center for Systems Biology and Personalized Medicine, Indiana University-Purdue University Indianapolis; Founder, MedeoLinx, Inc. Profiling Patients to Drive Biomarker Development N. R. Nirmala, Ph.D., Director, Biomarker Analysis and Informatics Unit, Translational Sciences, Novartis Institutes of Biomedical Research Panel: Informatics at R&D Interphases Moderator: Pearl S. Huang, Ph.D., Integrator, Oncology Franchise, Research & Early Development, Merck & Co. Image Analysis Considerations for Pre-clinical, in vivo Medical Imaging Matt Silva, Head, Imaging Sciences, Millennium, The Takeda Oncology Company RISe Prowler: A Semantic Web Approach to Integrating External and In-house Biology and Chemistry Information Ajay Shah, Ph.D., MBA, PMP, Director, Research Informatics, Elan Pharmaceuticals, Inc. Development of a Registration System for Biologics in a Collaborative Special Interest Group Jeremy Packer, Ph.D., Head, Bioinformatics, Abbott Semantic Web and Cloud Computing for Integrative Data Management and Analysis Infrastructure Jonas S. Almeida, Ph.D., Abell-Hanger Distinguished Professor, Bioinformatics and Computational Biology, University of Texas, M.D. Anderson Cancer Center How to Register: Telephone: 781-972-5400 Fax: 781-972-5425 Email: reg@healthtech.com To inquire about sponsorship and exhibit options, contact: Carol Dinerstein, 781-972-5471, dinerstein@healthtech.com or Jon Stroup, 781-972-5483, jstroup@healthtech.com Posted by: James Prudhomme Marketing Manager Cambridge Healthtech Institute 250 First Avenue, Suite 300 Needham, MA 02494 Direct: 781-972-5486 Fax: 781-972-5425 www.healthtech.com From andy from molsoft.com Thu Nov 19 17:32:08 2009 From: andy from molsoft.com (Andrew Orry) Date: Thu Nov 19 19:32:14 2009 Subject: [Computational-biology] Workshop: Modern Drug Target Crystallography and Structure Based Drug Discovery Message-ID: <4B05C768.5050107@molsoft.com> Dear All, MolSoft LLC ( www.molsoft.com ) and q.e.d. life science discoveries, inc., are conducting a joint two day workshop on Dec 14-15, 2009 at the Molsoft LLC facility in La Jolla, CA USA entitled "Modern Drug Target Crystallography and Structure Based Drug Design". The course will be taught by two experts in the field: Dr. Bernhard Rupp, crystallography textbook author and president of q.e.d. life science discoveries, and Dr. Ruben Abagyan, founder of Molsoft LLC and Professor of Pharmacology at the University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences. The provided course materials include a copy of the new and highly acclaimed textbook Biomolecular Crystallography: Principles, Practice, and Applications to Structural Biology. For more information please see: http://www.ruppweb.org/workshops/Molsoft_2009.htm -- Andrew Orry Ph.D. Senior Scientist MolSoft LLC 3366 North Torrey Pines Court Suite 300 La Jolla, CA 92037 U S A Phone: (858) 625-2000 (x108) Fax: (858) 625-2888 www.molsoft.com Latest ICM News: www.molsoft.com/news.html From prash from bioclues.org Fri Nov 20 03:28:02 2009 From: prash from bioclues.org (Prash) Date: Fri Nov 20 13:48:21 2009 Subject: [Computational-biology] The first Indian virtual conference on Bioinformatics 2010 (Inbix'10) Message-ID: <2bf36972-d6d5-488f-a964-1327754751e1@13g2000prl.googlegroups.com> Dear All, The first Indian virtual conference on Bioinformatics 2010 (Inbix'10): http://www.bioinformatics.org/wiki/Inbix10 Excellent opportunity to interact with leading scientists in the world in the area of Bioinformatics and Systems Biology! All for just Rs 500/- or 10 USD All the best Prash Prashanth Suravajhala C-DAC-Bioinformatics Group, Pune, India http://wiki.bioinformatics.org/prash I 'put a fullstop' as soon as I see myself complaining and blaming. These two habits destroy my inner power completely, because they show I am still expecting solutions and changes from others. Courtesy: Thought for Today From icaris from napier.ac.uk Mon Nov 23 08:54:30 2009 From: icaris from napier.ac.uk (icaris@napier.ac.uk) Date: Mon Nov 23 12:27:13 2009 Subject: [Computational-biology] CFP ICARIS 2010 9th International Conference on Artificial Immune Systems Message-ID: CALL FOR PAPERS ********************************************************************* ICARIS 2010 9th International Conference on Artificial Immune Systems 26th -- 29th July 2010, Edinburgh, UK http://www.artificial-immune-systems.org/icaris/2010/ ********************************************************************* AIMS & SCOPE Artificial immune systems (AIS) is a diverse and maturing area of research that bridges the disciplines of immunology and engineering. The scope of AIS ranges from modelling and simulation of the immune system through to immune-inspired algorithms and engineering solutions. In recent years, algorithms inspired by theoretical immunology have been applied to a wide variety of domains, including computer security, fault tolerance, data-mining and optimisation. Increasingly, theoretical insight into aspects of artificial and real immune systems has been sought through mathematical and computational modelling and analysis. The 9th International Conference on AIS (ICARIS) aims to build on the success of previous years to provide a forum for AIS researchers in academia and industry to present and discuss their latest advances. In addition to peer-reviewed papers, ICARIS will present a range of plenary lectures and tutorials to inspire and facilitate both the computer scientist and immunologist in their work. To encourage dialogue with the theoretical and clinical immunology communities, ICARIS 2010 will again adopt an (optional) extended abstract submission for the immune modelling stream. Full papers are welcome, but extended versions of abstracts will not be required. All accepted abstracts will be published alongside full papers in the proceedings. STREAMS The conference programme will be partitioned into three streams * Theoretical Stream This stream is for papers describing theoretical aspects of AIS, excluding theoretical immunology. This includes (but is not limited to) mathematical modelling of algorithms, convergence analysis, empirical investigation into algorithm performance and complexity analysis. To make sure the paper appeals to the widest possible audience, the mathematics should be clearly presented, and the paper should discuss the practical implications of any theoretical results. * Applied Stream This stream is for papers describing the application of AIS to computational and engineering problems. The problem domain should be clearly explained, detailing why it is challenging and why AIS are a suitable methodology to use. Experiments should be carefully explained, with the expectation that appropriate statistical analysis of results will be used to help draw conclusions. Where possible, the approach taken should be compared with alternative strategies. * Immune Modelling Stream This stream is for work detailing models and simulations of real and artificial immune systems. Authors are asked to be mindful of the inter-disciplinary nature of the forum when presenting their work. Extended abstracts or full papers are invited for submission. Both will undergo the same review process for quality and relevance. IMPORTANT DATES Paper Submission 24rd March 2010 Review Rebuttal Period 13th -- 17th April 2010 Final Decision 20th April 2010 Camera Ready Copies 30th April 2010 SUBMISSIONS Full papers should not be longer than 14 pages of LNCS, and extended abstracts for the modelling stream not more than 3 pages. Overly long submissions may be rejected at the reviewers discretion. All submissions should follow the formatting guidelines detailed by Springer http://www.springer.com/computer/lncs Following the reviews, a consultation period will be held, where authors will have 1 week to respond to reviewers comments if they wish. This is designed to increase the quality of papers, and remove any misunderstandings that may happen as part of the review process. See conference website for more submission details. LOCATION This year's ICARIS will be held in Scotland's historic capital, Edinburgh. A city with an international reputation in cultural events -- the ICARIS conference is squeezed between the International Film Festival and the Fringe, the biggest arts and comedy festival in the world. ORGANISING COMMITTEE General Chairs Emma Hart & Chris McEwan Stream Leaders Applied Stream Jon Timmis Immune Modelling Stream Stephanie Forrest Theoretical Stream Andy Hone Publicity Chair Mark Read From editor from gene-quantification.info Tue Nov 24 07:45:24 2009 From: editor from gene-quantification.info (Editor www.Gene-Quantification.info) Date: Tue Nov 24 12:19:23 2009 Subject: [Computational-biology] qPCR 2010 Event - Call for Abstracts Message-ID: qPCR 2010 Event - Call for Abstracts www.qPCR2010-Vienna.net ----------------------------------------------------- BioEPS GmbH is organizing the qPCR 2010 Event taking place April 7th – 9th, 2010 in Vienna, Austria. Scientists from all around the world will come to exchange ideas, share experiences, and discuss the exciting future of the perhaps most powerful analytical technology ever developed in the life sciences area – the quantitative real-time polymerase chain reaction (qPCR). We have the pleasure to announce the Call for Abstracts for the qPCR 2010 Event ! Finally we want to present 40 scientific talks from international scientists and diagnostic companies in the qPCR field who will show their latest research findings and newest technologies. The focus of the qPCR 2010 Event will be “The ongoing evolution of qPCR” representing all new and emerging techniques, applications and data analysis methods. Deadline is 31st January 2010 => http://submission.qPCR2010-Vienna.net Talk topics: -------------- MIQE and QM strategies in qPCR The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Following these guidelines will encourage better experimental practice, allowing more reliable and unequivocal interpretation of qPCR results. QM strategies in real- time PCR to guarantee better and more valid results. Keynote speaker: Prof. Stephen Bustin High throughput quantitative PCR – digital PCR 384 well applications, new high throughput platforms, droplet PCR, qPCR robotics, digital PCR, gene expression real-time RT-PCR arrays (mRNA and microRNA), quantitative multiplexing, … Keynote speaker: Prof. Mikael Kubista, Dr. Philip Day, Dr. Ken Livak HRM – High Resolution Melting SNP analysis, HRM = high resolution melt applications, Epigenetics, methylation markers, HRM platform comparison, etc … Keynote Speaker Prof. Carl Wittwer, Prof. Claudio Orlando Circulating nucleic acids Analysis of circulating RNAs and DNA and microRNAs as diagnostic and prognostic marker, … Speaker: Dr. Pamela Pinzani, Dr. Alfred Schöller, Dr. Jim Huggett Single–cell qPCR single-cell sampling, pre-amplification techniques, laser micro- dissection, sub-cellular PCR, micro-manipulation of cell clusters, cellular micro injection, FACS spotting, single cell handling, pre- amplification, … Keynote speaker: Dr. Michael W. Pfaffl, Dr. Anders Stahlberg RNAi – microRNA – siRNA Applications – miRNA normalisation RNAi mechanism, microRNA extraction, qRT-PCR technologies to detect microRNA, microRNA normalisation strategies, siRNA applications in combination with qRT-PCR, microRNA targets and microRNA precursors, new siRNA manipulation and microRNA technologies, Keynote speaker: Prof. Jo Vandesompele, Dr. Mirco Castoldi qPCR BioStatistics & BioInformatics software applications, data mining, calculation of relative expression, primer and probe design on mRNA and microRNA level, real- time PCR efficiency determination, mathematical modelling, multivariate expression profiling, statistics in real-time PCR, data management, multiway expression profiling, multiple regression analysis, 3D data visualization, ... Speaker: Dr. Ales Tichopad, Dr. Jan Hellemans, Dr. Anders Bergkvist An online registration and abstract submission software CONFTOOL is available here => http://registration.qPCR2010-Vienna.net ----------------------------- About qPCR: Using qPCR the amount of target nucleic acid in a complex sample can be determined with high precision, great accuracy, excellent specificity and the ultimate sensitivity of detecting a single molecule. The technique has revolutionized all molecular sciences and diagnostic applications. Conference presentations will include MIQE guidelines & QM strategies in qPCR, high performance nucleic acid extraction, single-cell applications, Epigenetics & High-Resolution- Melt analysis, circulating nucleic acids, and application involving RNAi and microRNA. Further developments of qPCR technology will be presented include improved instrumentation, miniaturization, high throughput platforms, cost efficacy, validity, flexibility, quality assessment and reliable Cq calculations, expression data comparisons, and interpretation. Today there is no field in the life sciences research, molecular biology and diagnostics areas that has not introduced qPCR technology for nucleic acid analysis. The combination with reverse transcription enables determination of mRNA, microRNA and widely opens the window for “Transcriptomics” – the first step of quantitative “Gene Expression Profiling” and “Functional Genomics”. An Industrial Exhibition will take place parallel to the symposium, with 32 leading biotechnology companies presenting their latest developments, including real-time PCR cyclers, NA extraction robots, consumables, new fluorescence dyes, NA detection and amplification chemistries, as well as real-time PCR data analysis software. For more information about the qPCR 2010 event contact Dr. Martina Reiter Martina.Reiter@bioeps.com Hope to meet you in April in Vienna! Michael Pfaffl