[Drosophila] New posting

[James Harvey]

Hello

I have a position to advertise, details as below:

_____________________________________________________________________________________________________________________________

Syngenta / Kelly Scientific Resources

Research Scientist (Two-Year Position)

      Understanding the mode of action and resistance risk associated with
novel insecticidal compounds is a key step in the development of new
crop-protection products.  This position involves both laboratory-based and
computational studies within a team which use genetic, physiological and
biochemical approaches to answer critical questions about the way small
molecules act on invertebrate pests.  The work will involve the handling of
chemicals, model organisms and pest insects.  Full training will be given
on all aspects of safe procedure.

      The job will involve working both independently and as part of a team
and  using  organisational  skills  to  work  flexibly  across  a number of
projects  simultaneously.  Projects will involve the application of genetic
approaches  in  model  or pest organisms to the study of pathophysiological
response  to  insecticide treatment or to the understanding of the basis of
insecticide resistance.

      The job holder will work within a team and provide bioinformatics and
molecular biology support for the team’s laboratory-based research program.
This may involve cloning work, construction of cDNA libraries, targeted
sequencing, or the building of constructs for generation of transgenic
invertebrates or for in-vitro expression.  Computer based research will
involve using bioinformatics tools to query genomic databases, identify
gene homologs, construct sequence alignments, and develop strategies for
mapping, cloning or building of constructs for transformation work.

      In addition the job holder may be required to assist with the design
and running of behavioural or electrophysiological assays aimed at
determining or monitoring mode of action or establishing the intrinsic
potencies of new lead chemicals.  The job holder will be able to deliver
high quality data to tight deadlines, to rapidly learn new tasks and have a
creative and scientific approach to problem solving.

      The   position   will   be   filled   by  someone  with  postgraduate
qualifications  and/or  practical  experience  in biological or biochemical
research.   They  will  have  practical  experience  of  molecular  biology
techniques  and  model  organism  genetics.  They will be computer literate
with  experience  of  using  bioinformatics and database tools.  Laboratory
experience  in any of the following areas would also be of value but is not
essential; microinjection, microscopy (esp. confocal or live-tissue calcium
imaging),   cell   or  tissue  culture,  electrophysiology,  Drosophila  or
C.elegans  behavioural  assays.   Good organisation skills and attention to
detail  are  required.  He  or  she  will  have  excellent written and oral
communication skills.

This role will be based at Syngenta, Jealott's Hill International Research
Centre, Bracknell, Berkshire.

For further information on this position please contact Jim Goodchild
(jim.goodchild from syngenta.com) 01344 416 451

To apply for this position please send a CV and covering letter to Kelly
Scientific Resources (ksr_london from kellyservices.co.uk)
020 7278 9809, Job ref. KS1

Closing date for applications 22nd July 2008.

_____________________________________________________________________________________________________________________________

Many thanks !

James Harvey
Consultant
Kelly Scientific Resources
1st Floor, New Premier House
150 Southampton Row
London WC1B 5AL

Tel   020 7278 9809
Fax  020 7278 9867

harveje from kellyservices.co.uk
www.kellyscientific.co.uk
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