[Employment] JobOpen: Scientist I-II, Cell-based Bioassay

[RS&A]

SCIENTIST I/II, Cell-based/Bioassay, #3001

 

Summary:

We are seeking a Scientist for the Bioassay Group within our client's
Analytical Biochemistry Department. The successful candidate will carry out
development, qualification and validation/transfer of cell-based bioassays
for biological characterization and testing of biopharmaceutical products,
such as humanized monoclonal antibodies and recombinant proteins. She/he
will take a leading role in the development, optimization, and validation of
a wide variety of cell-based assays, as well as identification and
evaluation of new technologies. The candidate will also be expected to be
familiar with SOP, GLP and GMP requirements. She/he will identify, evaluate
and optimize new cutting-edge technologies for improving efficiency of
in-process, release, and characterization bioactivity testing. She/he will
also contribute to the creation and review of documents such as development
reports, SOPs, validation protocols/reports, CMC regulatory filings (IND,
IMPD, BLA, etc.), and scientific journal publications. 


Position or Core Responsibilities:

The successful candidate will be expected to make detailed observations,
analyze data, interpret results, and exercise appropriate technical
discretion in the design, execution, and interpretation of experiments in an
independent manner. The candidate must have excellent written and oral
communication skills, good time management and organizational skills, and
previous supervisory experience. He/she will need to be able to solve
technical problems using an experimental approach (DOE) and develop new
characterization methods. The candidate will present and discuss
experimental results at group/project team meetings and scientific
conferences. Finally, he/she must be able to work in a team structure and
interface with different research and development departments. 

 

Essential Skills and Experience:

§  Candidate must have expertise and thorough understanding of cell-based
assay technologies and their application in the characterization for
biologics, such as assays used for ADCC, CDC, cellular signaling,
phosphorylation, receptor binding, cytokine secretion, cellular migration,
proliferation and apoptosis.

§  Molecular biology expertise in reporter gene technology is a must..

§  Experience with FACS, AlphaScreen, HTRF, BIAcore, MSD and automation is a
plus.

 

Education:

Ph.D. with 0 to 7 years of relevant experience, preferably working with
cell-based bioassay in a GLP/GMP industrial environment.

 

If you have an interest in this or other opportunities, please send your
resume as a MS Word compatible file attached to email to the attention of
Basirah at RS&A.  All correspondence is held in strict confidence. 

 

 
  _____  


(Ms) Basirah Al'Basit/Ann Rathbun
RS&A  Scientific Search
Sedona, AZ 86341 USA
 
TEL:  (928) 203-0074
EM:  RSA from sedona.net <blocked::mailto:RSA from sedona.net>