Hi. I am an undergraduate here at the University of Pennsylvania
and am looking for current theories, views, etc. on the topic of
self-non-self discrimination in the immature B cell population. Any
information that anyone can provide me with would be greatly appreciated.
I am especially curious if there are any parallels between T cell and B
cell tolerence induction with respect to required environmental conditions
(e.g. analagous factor in B cells differentiation to the thymus epithelial
cells responsible for selection of T cell populations). Please email the
responses to me directly. Thank you very much.
jkessler at mail.sas.upenn.edu