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question: monoclonal lymphocyte populations

cseabra at my-dejanews.com cseabra at my-dejanews.com
Thu Nov 5 13:05:37 EST 1998

I would like to know about the extent of normal immune responses.

The question is this:

if, in a patient of yours, you find in the periferal blood and in the
bone marrow a monoclonal population of lymphocytes, how many of them are
enought for you to consider the finding abnormal. We found a monoclonal B cell
population in pb-3% and bm-5% in a male 67 years old patient.

Are there completely monoclonal immune responses?
Can the more frequent epitopes in a normal immune response be present in
such numbers as to be mistaken for a neoplasic cell line?

I think not but I´m not sure.

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