In article <73pu5b$j5j at pmgm.Stanford.EDU>, jladasky at pmgm.Stanford.EDU
(John Ladasky) wrote:
> Hi there,
>> In our laboratory we often use Epstein-Barr virus (EBV) to create
> immortalized primate B cell cultures in vitro. I was wondering if there
> exist similar viruses that are known to transform mouse cells. Anyone
> know? Thanks!
I believe that polyoma virus will do this (but I'm no virologist
so you had better check). If I remember correctly only a small
number of genes (?large T, ?middle T) are required.
I hope that this is a start,
Bernard P. Murray, PhD
Dept. Cell. Mol. Pharmacol., UCSF, San Francisco, USA