Genetics question.....

Keith Robison robison at nucleus.harvard.edu
Tue Apr 11 08:27:55 EST 1995

ajmst37 at vms.cis.pitt.edu wrote:
: hello,

: I have a question regarding genetics.

: I was watching the show "Medicine Ball" tonite and was wondering about
: something.  Two dwarves had a child, and the father said that there was
: a one-in-four chance of the child being non-dwarf.  But if the parents
: are dwarves, does that not mean that they are both homozygous recessive?
: wouldn't this mean that there is no chance of the child being a non-dwarf?

: I'm only a sophmore in college, so I might just be undereducated on the
: subject.

: Very curious,

Don't always assume genetic disorders are recessive.  Achondroplasia,
a major form of genetic dwarfism, is dominant for dwarfism (and I
believe a recessive lethal).  Both parents are heterozygotes.

The best on-line resource for this  On-Line Mendelian Inheritance in Man (OMIM)

	E-mail		mailserv at gdb.org
	Gopher		gopher.gdb.org
	WWW		http://gdbwww.gdb.org/

It is a standard textbook on human genetic disease.

BTW  sci.bio or bionet.general are more appropriate for this sort
of question (_micro_biology is probably a particularly bad place to
put it)

Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI

robison at mito.harvard.edu 

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