Dear Netters,
I have a problem with the definition of sense and anit-sene RNA (DNA).
If a single-stranded RNA transcript has the sequence:
5-GGGCCCUUUAAAGGG-3
Then, the double-stranded DNA sequence from whence it came is:
5-GGGCCCTTTAAAGGG-3
3-CCCGGGAAATTTCCC-5
So, which is the sense strand, and which is the anti-sense strand???
My understanding is that the DNA strand which has the SAME sequence as the
RNA transcript (with the substitutions of T for U) is called the sense
strand, while the DNA strand with the COMPLEMENT sequence is known as
anti-sense.
PLEASE NOTE: I am looking for DEFINITIVE evidence (could you site a
reference, either a text book or favorite publication), not merely an
expert opinion.
Thanks in advace,
Dan
--
Daniel B. Oerther
Environmental Engineering
University of Illinois at Urbana-Champaign
205 N. Mathews Ave.
Urbana, IL 61801
U of I mail code: 250
voice: 217/ 333-6978
fax: 217/ 333-9464
web: http://www.cen.uiuc.edu/~oerther
