N.A. Joseph BMB2NAJ at leeds.ac.uk
Wed Mar 27 05:16:52 EST 1996

i have been examining the epidemiology and typing of MRSA for 2 years. has 
anyone compared the pulsed field gel electrophoresis patterns of MRSA ( using 
sma1 as the restriction enzyme) with the MSSA present in the same 
institution. could it be possible that these methicillin sensitive strains 
are capable of gaining the mecA gene by horizontal transfer? where did mecA 
originate from, was it really from E.coli. and is it really possible that 
this transfer of genes only occured once? evidence points against this view.
i would be grateful for any findings you have on the typing patterns of MRSA 
found within an institute

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