Post-doctoral research position available, in the laboratory of Dr. Abram
Gabriel at Rutgers University in Piscataway, New Jersey. We study a variety of
questions related to retrotransposon reverse transcriptases. These include:
1)Defining the connection between retrotransposon reverse transcriptases (yeast
Ty1, human L1, and Crithidia CRE1) and double-strand break repair in the yeast
Saccharomyces cerevisiae (see Teng, S. C., Kim, B., and Gabriel, A.
Retrotransposon reverse transcriptase-mediated repair of chromosomal breaks,
Nature, 383, 641-644, 1996)
2)Studying the molecular determinants of reverse transcriptase fidelity in yeast
(see Gabriel, A., Willems, M., Mules, E.H., and Boeke, J.D. Replication
infidelity during a single cycle of Ty1 retrotransposition, Proceedings of the
National Academy of Science, USA, 93, 7767 7771, 1996).
3)Examining the replication mechanisms of trypanosome site-specific non-LTR
retrotransposons (see Teng, S.C., Wang, X., and Gabriel, A. A new non-LTR
retrotransposon provides evidence for multiple distinct site-specific elements
in Crithidia fasciculata miniexon arrays, Nucleic Acids Research, 23, 2929-2936,
1995;
Interested applicants should contact:
Abram Gabriel
Dept. of Molecular Biology and Biochemistry
Rutgers University
CABM 306
679 Hoes Lane
Piscataway, NJ 08855
USA
908-235-5097(phone)
908-235-4880(fax)
gabriel at mbcl.rutgers.edu
