There was a lot of work done about 50 years agon under the guise of
PHAGE THERAPY - and also the control of bacteria in the milk industry
using bacteriophage. Several problems, including immunogenicity of the
proteinous bacteriophage or bacteriocins proved difficult to overcome. I
am not aware of progress using genetically engineered bacteriocins or
phage. I believe it is a promising area of research.
- O.A. Ogunseitan
University of California
Irvine, CA 92697-7070>
