> My problem is that we are occasionally asked to take blood assays to
> ascertain the therapeutic levels of Vancomycin, Phenytoin, Gentamycin
> and Digoxin. However there is some confusion as to when bloods should
> be drawn for these investigations.
At the hospital where I work, Vancomycin peak levels are obtained about
one hour after a one hour infusion, trough levels are just prior to the
next dose; gentamycin peak levels are obtained 1/2 hour after a 1/2 hour
infusion, trough levels are just prior to the next dose; digoxin levels
are obtained randomly once the steady state is reached; phenytoin levels
are obtained at least one hour after a loading infusion or 24 hours
after an oral bolus, phenytoin maintenance levels are obtained after 4
to 5 half-lives.
Hope this helps. If you need more information, you might try posting on
the newsgroup SCI.MED.PHARMACY
-Jim
--
_______________________________________________________________________
Jim Seaboldt, PharmD
http://www.mcn.net/~seaboldt/
Clinical Coordinator - Pharmacy | Clinical Assistant Professor
Benefis Health Care | University of Montana
Great Falls, Montana | Missoula, Montana
|
mailto:seaboldt at mcn.net | mailto:seaboldt at selway.umt.edu
_______________________________________________________________________
We Didn't Fight to the Top of the Food Chain Just to be Vegetarians
