I would try books on physical biochemistry. One that I came across recently was:
Physical Biochemistry, Principles and Applications by David Sheehan
(ISBN 0471986631). It has a chapter devoted to the physical basis of
electrophoresis (various kinds). Yes, it has a good list of references.
Gavin Chan
Earth & Planetary Sciences Tel: (314) 935-4080
Washington University Fax: (314) 935-7361
Campus Box 1169 email: gavin at zonvark.wustl.edu
One Brookings Dr. www: http://levee.wustl.edu/~chan
St. Louis, MO 63130-4899
Urs Lewandrowski wrote:
> Hi,
>> I´m looking for the chemical principle behind denaturating formaldehyde gel
> electrophoresis (agarose gels for RNA identification). Does anyone know, how
> exactly the formaldehyde interacts with RNA or where the denaturating effect
> comes from? A link to tech. lit (primary literature) would be best!
>> Thanks
>> Urs Lewandrowski
>urs.lewandrowski at ruhr-uni-bochum.de
