[Microbiology] Re: deletin mutation and phenotype expression

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"Bob" <bbx107.XYZ from excite.XYZ.com> wrote in message 
news:poak65dmp4c8d4ahj406nufpfqe28ghtqk from 4ax.com...
> On Fri, 24 Jul 2009 22:53:45 +0530, Kanchanadevi k <kdevik from gmail.com>
> wrote:
>
>> hi everyone
>>
>>
>>There is one mutant bacterial strain which is mutated by deletion mutation
>>of particular gene
>>even after deletion mutation it's reported that this mutant strain can
>>express that phenotype in minimal amount.
>>
>>so can any one tell me
>>how is this possible the gene responsible for particular metabolite is
>>deleted but still it's produces minimal amount of that metabolite.
>
>
> It would be best to consider the specific case. Can you give a
> reference for this.
>
> But briefly in general...
>
> Is it really true? Are the analyses correct? Not always easy.
>
> If really true, then there may be a 2nd gene that can compensate. This
> is the case for Lac+ strains of E coli derived after total deletion of
> the original lactase.
>
> bob
>

An interesting question and a good reply by Bob but sadly no response from 
the originator...now I cant sleep !


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