Re: the Large ORF by Jonathan Walker;
The largest ORF I am aware of is the Alpha-2-macroglobulin/Lipoprotein receptor
cloned by Joachim Herz et al (EMBO J 1988 7,4119-4127) with an open reading
frame of 4544 codons or 13632 bases. The total human cDNA isolated was
14896 bp. We have isolate the homologous mouse cDNA and it has about the
same size (14857 bp).
Fred Van Leuven Center for Human Genetics
Campus Gasthuisberg ON 6
B3000 Leuven Belgium.