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FRED at blekul13.bitnet FRED at blekul13.bitnet
Mon Sep 2 04:26:36 EST 1991

Re: the Large ORF by Jonathan Walker;

The largest ORF I am aware of is the Alpha-2-macroglobulin/Lipoprotein receptor
cloned by Joachim Herz et al (EMBO J 1988 7,4119-4127) with an open reading
frame of 4544 codons or 13632 bases. The total human cDNA isolated was
14896 bp. We have isolate the homologous mouse cDNA and it has about the
same size (14857 bp).

Anything bigger?

Fred Van Leuven  Center for Human Genetics
                 Campus Gasthuisberg ON 6
                 B3000 Leuven  Belgium.

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