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Phylogenetic Distribution of Trans-Splicing

Keith Robison robison1 at husc10.harvard.edu
Tue Apr 28 10:30:27 EST 1992

Okay, this one came up in a discussion today.  Would anyone care
to speculate as to why trans-splicing of mRNAs have such a wierd
wierd phylogenetic distribution.  As far as I know, the only proven
cases are in Trypanosome, C.elegans, and the chloroplast of Chlamydomonas.
It probably also occurs in Euglena.  In Trypanosomes and C.elegans, trans
splicing appears to be widespread and it may also be common in Euglena, so
why is it seemingly present in only these lineages?

Keith Robison
Harvard University
Program in Biochemistry, Molecular, Cellular, and Developmental Biology

robison at ribo.harvard.edu 

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