In article <1992Aug24.161335.730 at crc.ac.uk> gwilliam at crc.ac.uk
(Gary Williams x3294) writes:
|The latest values I have for the genome sizes and number of genes
|of species in the various genome programs are:
||Species Genome size No. of genes
||E.coli 4.7 Mbp 2,500 to 5,000
The person who gave you the number 5000 did not document it. I think
it is a guess and should not be used. 2500 is a better estimate.
|Yeast 14 Mbp 8,000
|> @inproceedings{Fangman1981,
|> author = "W. L. Fangman
|> and V. A. Zakian",
|> editor = "J. N. Strathern and E.W. Jones and J. R. Broach",
|> title = "MISSING",
|> booktitle = "The Molecular Biology of the Yeast Sacchromyces",
|> publisher = "Cold Spring Harbor Laboratory",
|> pages = "28-28",
|> comment = "size of yeast genome is 14000 kbp +/- 20%",
|> year = "1981"}
Good grief, I don't know where my student got this from! I have the
book right here and there is nothing on pages 28, the date is 1982, not 1981!
I think he messed up. Anyway, this is a better reference:
@article{Link1991,
author = "A. J. Link
and M. V. Olson",
title = "Physical Map of the {{\em Saccharomyces cerevisiae}}
Genome at 110-Kilobase Resolution",
journal = "Genetics",
volume = "127",
pages = "681-698",
year = "1991"}
Assuming that rDNA takes 2 to 3 x 10^6 bp, we calculate from the data
in that paper: 1.50E+07 +/- 5.13E+05 bp. From this estimate and
assuming the frequency of genes is that of orfs found by Oliver et al
(Nature 357: 38 (1992)) is 182/315357, I find an estimate for
the number of genes as 8651 +/- 296.
Of course, all these numbers are important and useful for doing
an information theory analysis.
Tom Schneider
National Cancer Institute
Laboratory of Mathematical Biology
Frederick, Maryland 21702-1201
toms at ncifcrf.gov
