A very rich resource is previous threads on this topic in this newsgroup.
If you go to IUBIO's !!wonderful!! gopher site (ftp.bio.indiana.edu) and
search the Network News for "directed and evolution" you will find the
postings.
Have fun!!
Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI
robison at biosun.harvard.edu