I wonder if someone could help me with a small problem. I'm writing an essay
on oncogenes and cell transformation and there is one thing I find unclear
in the references I am using. According to the 2nd edition of The Cell
(Alberts & co.) oncogenic mutations are always dominant, while tumor
suppressor gene (anti-oncogenic) mutations are always reccesive. Another
reference seems to indicate the possibility of recessive oncogenic mutations
(this could be a misunderstanding on my behalf).
Can an oncogenic mutation be reccesive? And if not, why?
Agnar Helgason, Iceland.