IUBio

Dosage compensation in Z/W chromosome systems

Keith Robison robison1 at husc10.harvard.edu
Thu Jan 7 19:02:09 EST 1993


FORSDYKE at QUCDN.QueensU.CA writes:


>    I am looking for recent work on dosage compensation in birds, butterflies,
>snakes and other species with Z/W chromosome systems. The best references I
>have are Johnson and Turner (1979) Heredity 43, 71-77 and
>         Baverstock et al., (1982) Nature 296, 763-766.
>    I will be checking the Science Citation Index to see who is citing these
>papers now but there may be some papers I miss. Can anyone help?
>                                             Sincerely,
>                                                       Don Forsdyke



Uh, could you enlighten me as to why Z/W systems need dosage compensation
-- I thought the Z/W meant that the two chromosomes contained the
same genes except for the sex-determination factor.

You might also look into work on C.elegans and speculations as
to the evolution of dosage compensation and hermaphrodism there.
I believe Jonathon Hodgkin is a major author in the field.

(a really fuzzy thought -- I think I saw some speculation on
chromosomal sex determination recently in a "review" journal
-- Current Biology, Current Opinion in Genes and Development,
Trends in Genetics, or Bioessays [most likely Bioessays]).


Keith Robison
Harvard University
Department of Cellular & Developmental Biology
Department of Genetics / HHMI

robison at biosun.harvard.edu 



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