Fist of all I would like to thank the people who have sent to myself,
as well as the news group, information in reply to my posting on directed
mutations from my posting of last week.
Secondly, I received E-mail from Terry Morse on the topic of
directed genectic mutations. He is unable at present to do any posting
on the USERNET, so he asked if I could help him out by posting for him.
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Date: Tue, 16 Mar 1993 11:54:33 -0800
To: sdryden at mta.ca
From: tmorse%
Subject: directed evolution
Cc: morset at ccmail.orst.edu
Stephen:
I just ran across an article which relates to your question, "Genetic
Response of Microbes to Extreme Challenges," by Arthur L. Koch (Journal
of Theoretical Biology (1993) 160, 1-21). His abstract reads, in part:
... [B]acteria have evolved in an environment that has
fluctuated so often in the past that they may have evolved a
group of "last ditch" mechanisms to meet these challenges.
These include developing a metabolically inactive state;
activating previously evolved, bu silent genes; increasing rates
of mutation under dire condition; and favoring movement of
exogenous and endogenous genetic elements. Some of these
processes can function to make it appear that directed "
Lamarckian" mutations have occurred. Together these survival
mechanisms constitute the "catastrophe insurance" of the cells.
Since I am not set up to post on Usenet, perhaps you will pass this
information on to the group.
Regards,
Terry Morse
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My appologies to Mr. Cairns for stating that he was involved in
scintific work at Princeton instead of Harvard, although I've heard that
Mr. Cairns has retired to England during the past year.
Stephen Dryden
Mount Alison University, Sackville N.B. Canada
sdryden at mta.ca
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++ Any more replies would be greatly appreciated . Thanks.. ++
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"To quote or not to quote, that is the filler.
Whether 'tis nobler in the mind to suffer the sling and arrows,
or by opposing them, use someone elses words."
