Brian,
With regard to the evolution of the mouse and human genomes and CpG islands
there is a reference of interest in P.N.A.S Vol.90, No.24 pp11995-11999
written by Francisco Antequera and Adrian Bird.
This journal has just arrived in our library so apologies if you already
have the reference.
Julian.
E-mail: HISCOX at AFRC.AC.UK
PS: Without bench work you wouldn't have sequence data etc!